Who are Cortef's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Cortisol, Emflaza, Fluocinolone Acetonide, Arnuity Ellipta, Lotemax, Pandel.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Cortef — Competitive Intelligence Brief

Cortef (hydrocortisone) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Corticosteroid [EPC]. Area: Oncology.

marketed Corticosteroid [EPC] Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Cortef (hydrocortisone) — Generic (originally Merck/Upjohn).

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Cortef TARGET	hydrocortisone	Generic (originally Merck/Upjohn)	marketed	Corticosteroid [EPC]	Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible	1952-01-01
Cortisol	Cortisol	University of Zurich	marketed		Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible
Emflaza	DEFLAZACORT	Ptc Therap	marketed	Corticosteroid [EPC]		2017-01-01
Fluocinolone Acetonide	FLUOCINOLONE	Eurofarma	marketed	Corticosteroid [EPC]		2016-01-01
Arnuity Ellipta	FLUTICASONE FUROATE	Haleon Us Holdings	marketed	Corticosteroid	Glucocorticoid receptor	2007-01-01
Lotemax	LOTEPREDNOL ETABONATE	Bausch Health	marketed	Corticosteroid	Glucocorticoid receptor	1998-01-01
Pandel	HYDROCORTISONE PROBUTATE	ANI Pharmaceuticals	marketed	Corticosteroid	Glucocorticoid receptor	1997-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2032-11-19 — Cortef · 9717740 · Method of Use · US
2033-01-10 — Cortef · 9675559 · Method of Use · US
2033-05-03 — Lotemax · 10058511 · Formulation · US
2033-05-03 — Lotemax · 9056057 · Formulation · US
2033-05-03 — Lotemax · 11219596 · Method of Use · US
2033-05-03 — Lotemax · 11219597 · Method of Use · US
2033-05-03 — Lotemax · 11596599 · Method of Use · US
2033-05-03 — Lotemax · 10857096 · Method of Use · US
2033-05-03 — Lotemax · 10864219 · Method of Use · US
2033-05-03 — Lotemax · 10945948 · Method of Use · US
2033-05-03 — Lotemax · 10940108 · Method of Use · US
2033-05-03 — Lotemax · 9737491 · Method of Use · US
2033-05-03 — Lotemax · 9827191 · Formulation · US
2033-05-03 — Lotemax · 10993908 · Method of Use · US
2033-05-03 — Lotemax · 12115246 · Formulation · US
2033-05-03 — Lotemax · 10688045 · Formulation · US
2033-05-03 — Lotemax · 11642317 · Formulation · US
2033-05-03 — Lotemax · 10646437 · Formulation · US
2033-05-03 — Lotemax · 9393213 · Formulation · US
2033-05-03 — Lotemax · 10646436 · Formulation · US
2033-05-03 — Lotemax · 11872318 · Formulation · US
2033-05-03 — Lotemax · 9532955 · Method of Use · US
2034-05-12 — Cortef · 9649280 · Formulation · US
2036-01-26 — Lotemax · 11534395 · Formulation · US
2036-12-23 — Lotemax · 10596107 · Formulation · US
2043-02-23 — Cortef · 11904046 · Formulation · US
2043-02-23 — Cortef · 12133914 · Method of Use · US

Sponsor landscape (Corticosteroid [EPC] class)

Eurofarma · 2 drugs in this class
· 2 drugs in this class
Astellas Pharma · 1 drug in this class
AstraZeneca K.K. · 1 drug in this class
Generic (originally Merck) · 1 drug in this class
Generic (originally Merck/Upjohn) · 1 drug in this class
Generic (originally Schering) · 1 drug in this class
National Jewish Health · 1 drug in this class
Padagis Us · 1 drug in this class
Ptc Therap · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cortef — Competitive Intelligence Brief. https://druglandscape.com/ci/hydrocortisone. Accessed 2026-05-14.

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