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HMS5552 — Competitive Intelligence Brief

HMS5552 (HMS5552) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Glucokinase activator. Area: Diabetes.

phase 3 Glucokinase activator Glucokinase (GCK) Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

HMS5552 (HMS5552) — Hua Medicine Limited. HMS5552 is a glucokinase activator that enhances glucose sensing and insulin secretion in pancreatic beta cells.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
HMS5552 TARGET HMS5552 Hua Medicine Limited phase 3 Glucokinase activator Glucokinase (GCK)
MK-6072 MK-6072 Merck Sharp & Dohme LLC phase 3 Glucokinase activator Glucokinase (GCK)
GK567 GK567 Galderma R&D phase 3 Glucokinase activator Glucokinase (GCK)
Placebo to MK-8527 Placebo to MK-8527 Merck Sharp & Dohme LLC phase 3 Glucokinase activator Glucokinase (GCK)
AZD0585 AZD0585 AstraZeneca phase 3 Glucokinase activator Glucokinase (GCK)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Glucokinase activator class)

  1. Merck Sharp & Dohme LLC · 2 drugs in this class
  2. Array BioPharma · 1 drug in this class
  3. AstraZeneca · 1 drug in this class
  4. Galderma R&D · 1 drug in this class
  5. Hua Medicine Limited · 1 drug in this class

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Cite this brief

Drug Landscape (2026). HMS5552 — Competitive Intelligence Brief. https://druglandscape.com/ci/hms5552. Accessed 2026-05-13.

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