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HMS5552 — Competitive Intelligence Brief
phase 3
Glucokinase activator
Glucokinase (GCK)
Diabetes
Small molecule
Live · refreshed every 30 min
Target snapshot
HMS5552 (HMS5552) — Hua Medicine Limited. HMS5552 is a glucokinase activator that enhances glucose sensing and insulin secretion in pancreatic beta cells.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| HMS5552 TARGET | HMS5552 | Hua Medicine Limited | phase 3 | Glucokinase activator | Glucokinase (GCK) | |
| MK-6072 | MK-6072 | Merck Sharp & Dohme LLC | phase 3 | Glucokinase activator | Glucokinase (GCK) | |
| GK567 | GK567 | Galderma R&D | phase 3 | Glucokinase activator | Glucokinase (GCK) | |
| Placebo to MK-8527 | Placebo to MK-8527 | Merck Sharp & Dohme LLC | phase 3 | Glucokinase activator | Glucokinase (GCK) | |
| AZD0585 | AZD0585 | AstraZeneca | phase 3 | Glucokinase activator | Glucokinase (GCK) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Glucokinase activator class)
- Merck Sharp & Dohme LLC · 2 drugs in this class
- Array BioPharma · 1 drug in this class
- AstraZeneca · 1 drug in this class
- Galderma R&D · 1 drug in this class
- Hua Medicine Limited · 1 drug in this class
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Cite this brief
Drug Landscape (2026). HMS5552 — Competitive Intelligence Brief. https://druglandscape.com/ci/hms5552. Accessed 2026-05-13.
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