Who are HMI-115's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): AVELUMAB, DURVALUMAB, Pf-06835375, Avelumab (MSB0010718C), Pf-06865571, Adebrelimab combined with SOX regimen.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

HMI-115 — Competitive Intelligence Brief

HMI-115 (HMI-115) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PD-L1 inhibitor. Area: Oncology.

phase 3 PD-L1 inhibitor PD-L1 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

HMI-115 (HMI-115) — Hope Medicine (Nanjing) Co., Ltd. HMI-115 is a humanized monoclonal antibody that targets and inhibits PD-L1, blocking its interaction with PD-1 and B7.1 to enhance anti-tumor immune responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
HMI-115 TARGET	HMI-115	Hope Medicine (Nanjing) Co., Ltd	phase 3	PD-L1 inhibitor	PD-L1
AVELUMAB	AVELUMAB		marketed	Programmed Death Ligand-1 Blocker [EPC]	PD-L1	2017-01-01
DURVALUMAB	DURVALUMAB		marketed	Programmed Death Ligand-1 Blocker [EPC]	PD-L1	2017-01-01
Pf-06835375	pf-06835375	Pfizer	marketed	Immunotherapy	PD-L1
Avelumab (MSB0010718C)	avelumab-msb0010718c	Pfizer	marketed	Monoclonal antibody	PD-L1
Pf-06865571	pf-06865571	Pfizer	marketed	Monoclonal antibody	PD-1/PD-L1 pathway
Adebrelimab combined with SOX regimen	Adebrelimab combined with SOX regimen	Yang Jianjun, PhD	marketed	PD-L1 inhibitor	PD-L1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PD-L1 inhibitor class)

Biocad · 13 drugs in this class
Shanghai Henlius Biotech · 8 drugs in this class
Celltrion · 5 drugs in this class
Mabwell (Shanghai) Bioscience Co., Ltd. · 4 drugs in this class
AstraZeneca · 4 drugs in this class
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. · 2 drugs in this class
Innovent Biologics (Suzhou) Co. Ltd. · 2 drugs in this class
Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
Shanghai Hengrui Pharmaceutical Co., Ltd. · 2 drugs in this class
CStone Pharmaceuticals · 1 drug in this class

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Cite this brief

Drug Landscape (2026). HMI-115 — Competitive Intelligence Brief. https://druglandscape.com/ci/hmi-115. Accessed 2026-05-13.

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