Who are HLD200's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Chidamide+ Fulvestrant, Romidepsin + CHOP, VDPHL01, HBI-8000 in combination with nivolumab, VDPHL01 QD, SHR2554; Chidamide analog tablets.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

HLD200 — Competitive Intelligence Brief

HLD200 (HLD200) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: HDAC inhibitor. Area: Oncology.

phase 3 HDAC inhibitor Histone deacetylase (HDAC) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

HLD200 (HLD200) — Ironshore Pharmaceuticals and Development, Inc. HLD200 is a histone deacetylase (HDAC) inhibitor that modulates gene expression by blocking HDAC enzymes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
HLD200 TARGET	HLD200	Ironshore Pharmaceuticals and Development, Inc	phase 3	HDAC inhibitor	Histone deacetylase (HDAC)
Chidamide+ Fulvestrant	Chidamide+ Fulvestrant	Liaoning Cancer Hospital & Institute	marketed	HDAC inhibitor + selective estrogen receptor degrader (combination therapy)	Histone deacetylases (HDAC) + Estrogen receptor alpha (ERα)
Romidepsin + CHOP	Romidepsin + CHOP	The Lymphoma Academic Research Organisation	phase 3	HDAC inhibitor + chemotherapy combination	Histone deacetylases (HDAC)
VDPHL01	VDPHL01	Veradermics, Inc.	phase 3	HDAC inhibitor	H3 histone deacetylase (HDAC)
HBI-8000 in combination with nivolumab	HBI-8000 in combination with nivolumab	HUYABIO International, LLC.	phase 3	HDAC inhibitor (in combination with PD-1 inhibitor)	Histone deacetylase (HDAC); combined with PD-1
VDPHL01 QD	VDPHL01 QD	Veradermics, Inc.	phase 3	HDAC inhibitor	H3 histone deacetylase (HDAC)
SHR2554; Chidamide analog tablets	SHR2554; Chidamide analog tablets	Jiangsu HengRui Medicine Co., Ltd.	phase 3	HDAC inhibitor	HDAC

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (HDAC inhibitor class)

Veradermics, Inc. · 2 drugs in this class
Ironshore Pharmaceuticals and Development, Inc · 1 drug in this class
Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
Melinta Therapeutics, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). HLD200 — Competitive Intelligence Brief. https://druglandscape.com/ci/hld200. Accessed 2026-05-13.

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