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Higher-volume C1-esterase inhibitor — Competitive Intelligence Brief

Higher-volume C1-esterase inhibitor (Higher-volume C1-esterase inhibitor) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Serine protease inhibitor / Complement regulator. Area: Immunology / Rare Disease.

phase 3 Serine protease inhibitor / Complement regulator C1-esterase (C1s), Factor XIIa, Plasma kallikrein Immunology / Rare Disease Biologic Live · refreshed every 30 min

Target snapshot

Higher-volume C1-esterase inhibitor (Higher-volume C1-esterase inhibitor) — CSL Behring. A higher-concentration formulation of C1-esterase inhibitor that suppresses activation of the contact system and complement cascade to prevent angioedema attacks.

Comparator set (1 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Higher-volume C1-esterase inhibitor TARGET Higher-volume C1-esterase inhibitor CSL Behring phase 3 Serine protease inhibitor / Complement regulator C1-esterase (C1s), Factor XIIa, Plasma kallikrein
Low-volume C1-esterase inhibitor Low-volume C1-esterase inhibitor CSL Behring phase 3 Serine protease inhibitor / Complement regulator C1-esterase inhibitor (C1-INH protein)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Serine protease inhibitor / Complement regulator class)

  1. CSL Behring · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Higher-volume C1-esterase inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/higher-volume-c1-esterase-inhibitor. Accessed 2026-05-16.

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