Who are High-Dose IFN-a2b's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Saphnelo, Besremi, Gamifant, Plegridy, Avonex, Betaseron.

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Last reviewed 2026-06-10 · How we verify

High-Dose IFN-a2b — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

High-Dose IFN-a2b (High-Dose IFN-a2b) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Interferon. Area: Oncology.

phase 3 Interferon Interferon-alpha receptor (IFNAR) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

High-Dose IFN-a2b (High-Dose IFN-a2b) — Peking University Cancer Hospital & Institute. High-dose interferon-alpha-2b activates the innate and adaptive immune system to enhance anti-tumor immunity and inhibit tumor cell proliferation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
High-Dose IFN-a2b TARGET	High-Dose IFN-a2b	Peking University Cancer Hospital & Institute	phase 3	Interferon	Interferon-alpha receptor (IFNAR)
Saphnelo	ANIFROLUMAB	AstraZeneca	marketed	Type I Interferon Receptor Antagonist [EPC]	Interferon alpha/beta receptor 1	2021-01-01
Besremi	ROPEGINTERFERON ALFA-2B	Pharma Essentia Corporation	marketed	Interferon alfa-2b [EPC]	Interferon alpha/beta receptor	2021-01-01
Gamifant	EMAPALUMAB	Novimmune S.A.	marketed	Interferon gamma Blocker [EPC]	Interferon gamma	2018-01-01
Plegridy	PEGINTERFERON BETA-1A	Biogen Idec Inc	marketed	Interferon beta [EPC]	Interferon alpha/beta receptor	2014-01-01
Avonex	INTERFERON BETA-1A	Biogen	marketed	Interferon beta [EPC]	Interferon alpha/beta receptor	1996-01-01
Betaseron	INTERFERON BETA-1B	Bayer Healthcare Pharms	marketed	Interferon beta	Interferon alpha/beta receptor	1993-01-01

Recent regulatory actions (last 90 days)

2026-04-24 — Saphnelo · FDA · approved · US · AstraZeneca

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Interferon class)

EMD Serono · 3 drugs in this class
Cinnagen · 2 drugs in this class
Tanabe Pharma Corporation · 2 drugs in this class
Biogen · 1 drug in this class
Celgene · 1 drug in this class
EMD Serono Research & Development Institute, Inc. · 1 drug in this class
Case Comprehensive Cancer Center · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Human Genome Sciences Inc. · 1 drug in this class
Bayer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). High-Dose IFN-a2b — Competitive Intelligence Brief. https://druglandscape.com/ci/high-dose-ifn-a2b. Accessed 2026-06-10.

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