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High Dose Enoxaparin — Competitive Intelligence Brief
marketed
Low-molecular-weight heparin (LMWH)
Coagulation factors Xa and IIa (via antithrombin III)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
High Dose Enoxaparin (High Dose Enoxaparin) — Oregon Health and Science University. High-dose enoxaparin is a low-molecular-weight heparin that inhibits blood coagulation by enhancing the activity of antithrombin III against factors Xa and IIa.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| High Dose Enoxaparin TARGET | High Dose Enoxaparin | Oregon Health and Science University | marketed | Low-molecular-weight heparin (LMWH) | Coagulation factors Xa and IIa (via antithrombin III) | |
| Usual dose adjustment of enoxaparin | Usual dose adjustment of enoxaparin | Assistance Publique - Hôpitaux de Paris | marketed | Low-molecular-weight heparin (LMWH) | Factor Xa and Factor IIa (via antithrombin III) | |
| Tinzaparin continuous infusion | Tinzaparin continuous infusion | Tampere University Hospital | marketed | Low-molecular-weight heparin (LMWH) | Antithrombin III (enhancer); Factor Xa and Factor IIa (indirect targets) | |
| dalteparin injection | dalteparin injection | University of Rochester | marketed | Low-molecular-weight heparin (LMWH) | Antithrombin III (Factor Xa and Factor IIa) | |
| Low dose nadroparin | Low dose nadroparin | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | marketed | Low-molecular-weight heparin (LMWH) | Factor Xa, Thrombin (Factor IIa) | |
| Intermediate dose dalteparin | Intermediate dose dalteparin | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | marketed | Low-molecular-weight heparin (LMWH) | Antithrombin III (indirect); Factor Xa and Thrombin (downstream targets) | |
| normal injection of Enoxaparine | normal injection of Enoxaparine | French Cardiology Society | marketed | Low-molecular-weight heparin (LMWH) | Factor Xa and Factor IIa (via antithrombin III enhancement) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Low-molecular-weight heparin (LMWH) class)
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · 7 drugs in this class
- University of Melbourne · 3 drugs in this class
- French Cardiology Society · 2 drugs in this class
- Ottawa Hospital Research Institute · 2 drugs in this class
- McMaster University · 2 drugs in this class
- Assistance Publique - Hôpitaux de Paris · 2 drugs in this class
- GlaxoSmithKline · 1 drug in this class
- IRCCS Azienda Ospedaliero-Universitaria di Bologna · 1 drug in this class
- Cristália Produtos Químicos Farmacêuticos Ltda. · 1 drug in this class
- Helsinki University Central Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). High Dose Enoxaparin — Competitive Intelligence Brief. https://druglandscape.com/ci/high-dose-enoxaparin. Accessed 2026-06-10.
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