Who are HAL 0.2% with illumination's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): BF-200 ALA cream, MAL, Placebo to BF-200 ALA gel, Metvix and conventional PDT, Heme arginate (Normosang), Metvix cream.

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Last reviewed 2026-06-10 · How we verify

HAL 0.2% with illumination — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

HAL 0.2% with illumination (HAL 0.2% with illumination) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Photodynamic therapy agent. Area: Oncology.

phase 2 Photodynamic therapy agent Aminolevulinic acid Oncology Small molecule Live · refreshed every 30 min

Target snapshot

HAL 0.2% with illumination (HAL 0.2% with illumination) — Photocure. Photodynamic therapy with aminolevulinic acid

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
HAL 0.2% with illumination TARGET	HAL 0.2% with illumination	Photocure	phase 2	Photodynamic therapy agent	Aminolevulinic acid
BF-200 ALA cream	BF-200 ALA cream	Joint Authority for Päijät-Häme Social and Health Care	marketed	Photodynamic therapy agent	Protoporphyrin IX (photosensitizer generated from aminolevulinic acid)
MAL	MAL	Photocure	marketed	Photosensitizing agent	Protoporphyrin IX (via aminolevulinic acid pathway)
Placebo to BF-200 ALA gel	Placebo to BF-200 ALA gel	Biofrontera Bioscience GmbH	phase 3	Photodynamic therapy agent	Protoporphyrin IX (via aminolevulinic acid metabolism)
Metvix and conventional PDT	Metvix and conventional PDT	Galderma R&D	phase 3	Photosensitizing agent	Protoporphyrin IX (via aminolevulinic acid pathway)
Heme arginate (Normosang)	Heme arginate (Normosang)	University of Edinburgh	phase 3	Heme supplement	Delta-aminolevulinic acid synthase 1 (ALAS1)
Metvix cream	Metvix cream	Galderma R&D	phase 3	Photosensitizing agent	Protoporphyrin IX (via aminolevulinic acid pathway)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Photodynamic therapy agent class)

Galderma R&D · 3 drugs in this class
DUSA Pharmaceuticals, Inc. · 2 drugs in this class
Biofrontera Bioscience GmbH · 2 drugs in this class
Steba Biotech S.A. · 2 drugs in this class
National Cancer Center, Korea · 1 drug in this class
Photocure · 1 drug in this class
Psoriasis Treatment Center of Central New Jersey · 1 drug in this class
Joint Authority for Päijät-Häme Social and Health Care · 1 drug in this class

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Cite this brief

Drug Landscape (2026). HAL 0.2% with illumination — Competitive Intelligence Brief. https://druglandscape.com/ci/hal-0-2-with-illumination. Accessed 2026-06-10.

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