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GW685698 — Competitive Intelligence Brief

GW685698 (GW685698) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: P2X7 receptor antagonist. Area: Immunology.

phase 3 P2X7 receptor antagonist P2X7 Immunology Small molecule Live · refreshed every 30 min

Target snapshot

GW685698 (GW685698) — GlaxoSmithKline. GW685698 is a selective antagonist of the P2X7 receptor, an ATP-gated ion channel involved in inflammatory and immune responses.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
GW685698 TARGET GW685698 GlaxoSmithKline phase 3 P2X7 receptor antagonist P2X7
OPC-6535 Tablets (drug) OPC-6535 Tablets (drug) Otsuka Pharmaceutical Development & Commercialization, Inc. phase 3 P2X7 receptor antagonist P2X7
OPC-6535 OPC-6535 Otsuka Pharmaceutical Co., Ltd. phase 3 P2X7 receptor antagonist P2X7
GW406381 GW406381 GlaxoSmithKline phase 3 P2X7 receptor antagonist P2X7

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (P2X7 receptor antagonist class)

  1. GlaxoSmithKline · 2 drugs in this class
  2. Akros Pharma Inc. · 1 drug in this class
  3. Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class
  4. Otsuka Pharmaceutical Development & Commercialization, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). GW685698 — Competitive Intelligence Brief. https://druglandscape.com/ci/gw685698. Accessed 2026-05-13.

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