Last reviewed · How we verify
GW685698 — Competitive Intelligence Brief
phase 3
P2X7 receptor antagonist
P2X7
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
GW685698 (GW685698) — GlaxoSmithKline. GW685698 is a selective antagonist of the P2X7 receptor, an ATP-gated ion channel involved in inflammatory and immune responses.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| GW685698 TARGET | GW685698 | GlaxoSmithKline | phase 3 | P2X7 receptor antagonist | P2X7 | |
| OPC-6535 Tablets (drug) | OPC-6535 Tablets (drug) | Otsuka Pharmaceutical Development & Commercialization, Inc. | phase 3 | P2X7 receptor antagonist | P2X7 | |
| OPC-6535 | OPC-6535 | Otsuka Pharmaceutical Co., Ltd. | phase 3 | P2X7 receptor antagonist | P2X7 | |
| GW406381 | GW406381 | GlaxoSmithKline | phase 3 | P2X7 receptor antagonist | P2X7 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (P2X7 receptor antagonist class)
- GlaxoSmithKline · 2 drugs in this class
- Akros Pharma Inc. · 1 drug in this class
- Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- GW685698 CI watch — RSS
- GW685698 CI watch — Atom
- GW685698 CI watch — JSON
- GW685698 alone — RSS
- Whole P2X7 receptor antagonist class — RSS
Cite this brief
Drug Landscape (2026). GW685698 — Competitive Intelligence Brief. https://druglandscape.com/ci/gw685698. Accessed 2026-05-13.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab