Who are GW642444 6.25's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Zegalogue, Low-Dose Glucagon, morphine and glucagon, Glucagon 12.5ng/kg/min, QVM149, CJ-30001/CJ-30002.

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Last reviewed 2026-05-16 · How we verify

GW642444 6.25 — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

GW642444 6.25 (GW642444 6.25) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Glucagon receptor antagonist. Area: Diabetes.

phase 2 Glucagon receptor antagonist Glucagon receptor Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

GW642444 6.25 (GW642444 6.25) — GlaxoSmithKline. GW642444 is a glucagon receptor antagonist.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
GW642444 6.25 TARGET	GW642444 6.25	GlaxoSmithKline	phase 2	Glucagon receptor antagonist	Glucagon receptor
Zegalogue	DASIGLUCAGON	Zealand Pharma	marketed	Antihypoglycemic Agent [EPC]	Glucagon receptor	2021-01-01
Low-Dose Glucagon	Low-Dose Glucagon	Steno Diabetes Center Copenhagen	marketed	Glucagon receptor agonist	Glucagon receptor (GCGR)
morphine and glucagon	morphine and glucagon	National Taiwan University Hospital	marketed	Opioid analgesic + glucagon (hormone)	Mu-opioid receptor (morphine); glucagon receptor (glucagon)
Glucagon 12.5ng/kg/min	Glucagon 12.5ng/kg/min	Cambridge University Hospitals NHS Foundation Trust	marketed	Glucagon receptor agonist	Glucagon receptor (GCGR)
QVM149	QVM149	Dr. Grace Parraga	phase 3	GLP-1 receptor agonist and glucagon receptor antagonist	GLP-1R, glucagon receptor
CJ-30001/CJ-30002	CJ-30001/CJ-30002	HK inno.N Corporation	phase 3	Dual GLP-1/GCG receptor agonist	GLP-1 receptor, Glucagon receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Glucagon receptor antagonist class)

Merck Sharp & Dohme LLC · 2 drugs in this class
Alizyme · 2 drugs in this class
Claes-Göran Östenson · 1 drug in this class
Gan and Lee Pharmaceuticals, USA · 1 drug in this class
GlaxoSmithKline · 1 drug in this class
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in this class
AbbVie (prior sponsor, Abbott) · 1 drug in this class
Novo Nordisk A/S · 1 drug in this class
Allergan · 1 drug in this class

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Cite this brief

Drug Landscape (2026). GW642444 6.25 — Competitive Intelligence Brief. https://druglandscape.com/ci/gw642444-6-25. Accessed 2026-05-16.

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