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GSK 1437173A — Competitive Intelligence Brief
phase 3
Phosphodiesterase 4 (PDE4) inhibitor
PDE4
Respiratory / Immunology
Biologic
Live · refreshed every 30 min
Target snapshot
GSK 1437173A (GSK 1437173A) — GlaxoSmithKline. GSK1437173A is a selective inhibitor of phosphodiesterase 4 (PDE4) that reduces inflammatory mediator production by increasing intracellular cAMP levels.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| GSK 1437173A TARGET | GSK 1437173A | GlaxoSmithKline | phase 3 | Phosphodiesterase 4 (PDE4) inhibitor | PDE4 | |
| Otezla | APREMILAST | Amgen | marketed | Phosphodiesterase 4 Inhibitor [EPC] | PDE4 | 2014-01-01 |
| Apremilast (CC-10004) | Apremilast (CC-10004) | Virginia Clinical Research, Inc. | marketed | Phosphodiesterase 4 (PDE4) inhibitor | PDE4 | |
| Crisaborole ointment, 2% | Crisaborole ointment, 2% | Pfizer | marketed | Phosphodiesterase 4 (PDE4) inhibitor | PDE4 | |
| Crisaborole Vehicle | Crisaborole Vehicle | Pfizer | marketed | Phosphodiesterase 4 (PDE4) inhibitor | PDE4 | |
| RPH-051 | RPH-051 | R-Pharm | phase 3 | PDE4 inhibitor | PDE4 | |
| MP513 | MP513 | Handok Inc. | phase 3 | PDE4 inhibitor | PDE4 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Phosphodiesterase 4 (PDE4) inhibitor class)
- Pfizer · 6 drugs in this class
- Shire · 3 drugs in this class
- Almirall, S.A. · 3 drugs in this class
- Arcutis Biotherapeutics, Inc. · 2 drugs in this class
- LEO Pharma · 2 drugs in this class
- ORA, Inc. · 1 drug in this class
- Tillotts Pharma AG · 1 drug in this class
- AbbVie (prior sponsor, Abbott) · 1 drug in this class
- Virginia Clinical Research, Inc. · 1 drug in this class
- Alfasigma S.p.A. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). GSK 1437173A — Competitive Intelligence Brief. https://druglandscape.com/ci/gsk-1437173a. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing