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Granisetron Injection — Competitive Intelligence Brief
phase 3
5-HT3 receptor antagonist
5-HT3 receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Granisetron Injection (Granisetron Injection) — Eye & ENT Hospital of Fudan University. Granisetron blocks serotonin 5-HT3 receptors on chemoreceptor trigger zone and vagal afferent nerves to prevent nausea and vomiting.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Granisetron Injection TARGET | Granisetron Injection | Eye & ENT Hospital of Fudan University | phase 3 | 5-HT3 receptor antagonist | 5-HT3 receptor | |
| Trintellix | vortioxetine | Takeda | marketed | Serotonin modulator and stimulator (SMS); SSRI-like agent | Serotonin transporter (SERT); 5-HT3 receptor; 5-HT1A receptor | 2013-01-01 |
| Ramosetron, Aprepitant, Dexamethasone | Ramosetron, Aprepitant, Dexamethasone | Hallym University Medical Center | marketed | 5-HT3 antagonist / NK1 antagonist / corticosteroid combination | 5-HT3 receptor, NK1 receptor, glucocorticoid receptor | |
| Ondansetron orodispersible film once | Ondansetron orodispersible film once | Chongqing University Cancer Hospital | marketed | 5-HT3 receptor antagonist | 5-HT3 receptor | |
| Venlafaxine XR + Mirtazapine | Venlafaxine XR + Mirtazapine | National Institute of Mental Health (NIMH) | marketed | Antidepressant combination (SNRI + NaSSA) | Serotonin transporter, norepinephrine transporter, alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors | |
| ramosetron, ondansetron, dexamethasone | ramosetron, ondansetron, dexamethasone | Government Medical College, Haldwani | marketed | 5-HT3 receptor antagonist + corticosteroid combination | 5-HT3 receptor (ramosetron, ondansetron); glucocorticoid receptor (dexamethasone) | |
| ondansetron (Zofran) | ondansetron (Zofran) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | marketed | 5-HT3 receptor antagonist | 5-HT3 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (5-HT3 receptor antagonist class)
- Helsinn Healthcare SA · 4 drugs in this class
- LG Life Sciences · 3 drugs in this class
- University of Malaya · 2 drugs in this class
- GlaxoSmithKline · 1 drug in this class
- Hamad Medical Corporation · 1 drug in this class
- Eye & ENT Hospital of Fudan University · 1 drug in this class
- Instituto Mexicano del Seguro Social · 1 drug in this class
- Chongqing University Cancer Hospital · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- MonoSol Rx · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Granisetron Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/granisetron-injection. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing