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Granisetron and dexamethasone — Competitive Intelligence Brief
phase 3
5-HT3 receptor antagonist + corticosteroid combination
5-HT3 receptor (granisetron); glucocorticoid receptor (dexamethasone)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Granisetron and dexamethasone (Granisetron and dexamethasone) — Guangxi Medical University. Granisetron blocks 5-HT3 receptors to prevent nausea and vomiting, while dexamethasone suppresses inflammatory cytokines and enhances antiemetic effects.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Granisetron and dexamethasone TARGET | Granisetron and dexamethasone | Guangxi Medical University | phase 3 | 5-HT3 receptor antagonist + corticosteroid combination | 5-HT3 receptor (granisetron); glucocorticoid receptor (dexamethasone) | |
| ramosetron, ondansetron, dexamethasone | ramosetron, ondansetron, dexamethasone | Government Medical College, Haldwani | marketed | 5-HT3 receptor antagonist + corticosteroid combination | 5-HT3 receptor (ramosetron, ondansetron); glucocorticoid receptor (dexamethasone) | |
| Placebo, Palonosetron, Dexamethasone | Placebo, Palonosetron, Dexamethasone | Azienda Ospedaliera di Perugia | phase 3 | 5-HT3 receptor antagonist + corticosteroid combination | 5-HT3 receptor (palonosetron); glucocorticoid receptor (dexamethasone) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (5-HT3 receptor antagonist + corticosteroid combination class)
- Azienda Ospedaliera di Perugia · 1 drug in this class
- Government Medical College, Haldwani · 1 drug in this class
- Guangxi Medical University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Granisetron and dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/granisetron-and-dexamethasone. Accessed 2026-05-16.
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