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GnRH agonist/antagonist — Competitive Intelligence Brief
marketed
GnRH agonist/antagonist
GnRH receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
GnRH agonist/antagonist (GnRH agonist/antagonist) — Memorial Sloan Kettering Cancer Center. GnRH agonists/antagonists suppress gonadotropin-releasing hormone signaling to reduce sex hormone production, used in oncology to manage hormone-sensitive cancers and their treatment side effects.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| GnRH agonist/antagonist TARGET | GnRH agonist/antagonist | Memorial Sloan Kettering Cancer Center | marketed | GnRH agonist/antagonist | GnRH receptor | |
| Lupron | leuprorelin | Accord Healthcare S.L.U. | marketed | Gonadotropin Releasing Hormone Receptor Agonist | GnRH receptors | 1985-01-01 |
| Micronor | norethisterone | Johnson & Johnson | marketed | Progestin | GnRH receptors | 1962-01-01 |
| Ganirelix Acetate, Cetrolix Acetate | Ganirelix Acetate, Cetrolix Acetate | Assaf-Harofeh Medical Center | marketed | GnRH antagonist | GnRH receptor | |
| Half-Dose Depot Triptorelin | Half-Dose Depot Triptorelin | Tehran University of Medical Sciences | marketed | GnRH agonist | GnRH receptor | |
| Degarelix (LHRH antagonist) | Degarelix (LHRH antagonist) | Rabin Medical Center | marketed | GnRH antagonist | GnRH receptor | |
| Leuprolide acetate in depot suspension | Leuprolide acetate in depot suspension | Colorado Center for Reproductive Medicine | marketed | GnRH agonist | GnRH receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GnRH agonist/antagonist class)
- Memorial Sloan Kettering Cancer Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). GnRH agonist/antagonist — Competitive Intelligence Brief. https://druglandscape.com/ci/gnrh-agonist-antagonist. Accessed 2026-05-17.
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