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Geodon (Ziprasidone) — Competitive Intelligence Brief
phase 3
Atypical antipsychotic
Dopamine D2 receptor, Serotonin 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Geodon (Ziprasidone) (Geodon (Ziprasidone)) — Pfizer's Upjohn has merged with Mylan to form Viatris Inc.. Ziprasidone is an atypical antipsychotic that blocks dopamine D2 and serotonin 5-HT2A receptors in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Geodon (Ziprasidone) TARGET | Geodon (Ziprasidone) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | phase 3 | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Quetiapine Fumarate Sustained Release | Quetiapine Fumarate Sustained Release | AstraZeneca | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Quetiapine or Risperidone + Aripiprazole | Quetiapine or Risperidone + Aripiprazole | Otsuka Pharmaceutical Development & Commercialization, Inc. | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor | |
| Fluoxetine+Olanzapine | Fluoxetine+Olanzapine | University Health Network, Toronto | marketed | SSRI + atypical antipsychotic combination | Serotonin transporter (SERT), dopamine D2 receptor, serotonin 5-HT2A receptor | |
| Olanzapine-Fluoxetine Combination | Olanzapine-Fluoxetine Combination | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| olanzapine + fluoxetine | olanzapine + fluoxetine | University of Florida | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| Lithium carbonate + perospirone hydrochloride | Lithium carbonate + perospirone hydrochloride | Shanghai Mental Health Center | marketed | Mood stabilizer + atypical antipsychotic combination | Inositol monophosphatase, GSK-3 (lithium); dopamine D2 receptor, serotonin 5-HT2A receptor (perospirone) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). Geodon (Ziprasidone) — Competitive Intelligence Brief. https://druglandscape.com/ci/geodon-ziprasidone. Accessed 2026-05-14.
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