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Gemcitabine with R115777 — Competitive Intelligence Brief
phase 3
Nucleoside analog + farnesyltransferase inhibitor combination
Ribonucleotide reductase (gemcitabine); farnesyltransferase (R115777)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Gemcitabine with R115777 (Gemcitabine with R115777) — Johnson & Johnson Pharmaceutical Research & Development, L.L.C.. Gemcitabine is a nucleoside analog that inhibits DNA synthesis, while R115777 is a farnesyltransferase inhibitor that blocks Ras protein activation, together targeting cancer cell proliferation through complementary pathways.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Gemcitabine with R115777 TARGET | Gemcitabine with R115777 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | phase 3 | Nucleoside analog + farnesyltransferase inhibitor combination | Ribonucleotide reductase (gemcitabine); farnesyltransferase (R115777) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleoside analog + farnesyltransferase inhibitor combination class)
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Gemcitabine with R115777 — Competitive Intelligence Brief. https://druglandscape.com/ci/gemcitabine-with-r115777. Accessed 2026-05-17.
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