Last reviewed · How we verify
Ztalmy — Competitive Intelligence Brief
marketed
Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC]
GABA A receptor alpha-2/beta-1/gamma-2
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Ztalmy (GANAXOLONE) — Marinus. Ztalmy works by enhancing the activity of the GABA A receptor, a key player in regulating the activity of neurons in the brain.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ztalmy TARGET | GANAXOLONE | Marinus | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] | GABA A receptor alpha-2/beta-1/gamma-2 | 2022-01-01 |
| Zurzuvae | ZURANOLONE | Biogen | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] | GABA A receptor alpha-4/beta-3/delta | 2023-01-01 |
| Zulresso | BREXANOLONE | Sage Therap | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator | GABA-A receptor alpha-1/beta-2/gamma-2 | 2019-01-01 |
| ZULRESSO® | ZULRESSO® | Supernus Pharmaceuticals, Inc. | marketed | Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator | GABA-A receptor alpha-1/beta-2/gamma-2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] class)
- Biogen · 1 drug in this class
- Marinus · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Ztalmy CI watch — RSS
- Ztalmy CI watch — Atom
- Ztalmy CI watch — JSON
- Ztalmy alone — RSS
- Whole Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] class — RSS
Cite this brief
Drug Landscape (2026). Ztalmy — Competitive Intelligence Brief. https://druglandscape.com/ci/ganaxolone. Accessed 2026-05-15.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab