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Ztalmy — Competitive Intelligence Brief

Ztalmy (GANAXOLONE) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC]. Area: Neuroscience.

marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] GABA A receptor alpha-2/beta-1/gamma-2 Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Ztalmy (GANAXOLONE) — Marinus. Ztalmy works by enhancing the activity of the GABA A receptor, a key player in regulating the activity of neurons in the brain.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ztalmy TARGET GANAXOLONE Marinus marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] GABA A receptor alpha-2/beta-1/gamma-2 2022-01-01
Zurzuvae ZURANOLONE Biogen marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] GABA A receptor alpha-4/beta-3/delta 2023-01-01
Zulresso BREXANOLONE Sage Therap marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator GABA-A receptor alpha-1/beta-2/gamma-2 2019-01-01
ZULRESSO® ZULRESSO® Supernus Pharmaceuticals, Inc. marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator GABA-A receptor alpha-1/beta-2/gamma-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator [EPC] class)

  1. Biogen · 1 drug in this class
  2. Marinus · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ztalmy — Competitive Intelligence Brief. https://druglandscape.com/ci/ganaxolone. Accessed 2026-05-15.

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