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Aryplase — Competitive Intelligence Brief

Aryplase (GALSULFASE) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC]. Area: Metabolic.

marketed Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] Metabolic Enzyme Live · refreshed every 30 min

Target snapshot

Aryplase (GALSULFASE) — BioMarin. Aryplase breaks down accumulated glycosaminoglycans in lysosomes to treat Maroteaux-Lamy syndrome.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Aryplase TARGET GALSULFASE BioMarin marketed Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 2005-01-01
Rhgalns ELOSULFASE ALFA BioMarin marketed Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] N-acetylgalactosamine-6-sulfatase 2014-01-01
Elaprase IDURSULFASE Takeda marketed Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 2006-01-01
Aldurazyme LARONIDASE BioMarin marketed Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] 2003-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] class)

  1. BioMarin · 3 drugs in this class
  2. Takeda · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Aryplase — Competitive Intelligence Brief. https://druglandscape.com/ci/galsulfase. Accessed 2026-05-13.

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