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Horizant — Competitive Intelligence Brief
marketed
Anti-epileptic Agent
Voltage-dependent calcium channel subunit alpha-2/delta-1
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Horizant (GABAPENTIN ENACARBIL) — Azurity. Horizant works by binding to the alpha-2/delta-1 subunit of voltage-dependent calcium channels, reducing the release of excitatory neurotransmitters and alleviating pain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Horizant TARGET | GABAPENTIN ENACARBIL | Azurity | marketed | Anti-epileptic Agent | Voltage-dependent calcium channel subunit alpha-2/delta-1 | 2011-01-01 |
| Tarlige | MIROGABALIN | Daiichi Sankyo | marketed | Voltage-dependent calcium channel subunit alpha-2/delta-1 | ||
| Horizant | Horizant | University of Missouri-Columbia | marketed | Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent calcium channel subunit alpha-2/delta-2 | ||
| OXCARBAZEPINE | OXCARBAZEPINE | marketed | Anti-epileptic Agent [EPC] | 2000-01-01 | ||
| Gabitril | TIAGABINE | Cephalon | marketed | Anti-epileptic Agent | Sodium- and chloride-dependent GABA transporter 1 | 1997-01-01 |
| Cerebyx | FOSPHENYTOIN | Pfizer | marketed | Anti-epileptic Agent | Sodium channel protein type 5 subunit alpha | 1996-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
Recent regulatory actions (last 90 days)
- — OXCARBAZEPINE · FDA · approved · US
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anti-epileptic Agent class)
- Pfizer · 2 drugs in this class
- Azurity · 1 drug in this class
- Cephalon · 1 drug in this class
- Novartis · 1 drug in this class
- Recordati · 1 drug in this class
- Viatris · 1 drug in this class
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- Horizant CI watch — RSS
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Cite this brief
Drug Landscape (2026). Horizant — Competitive Intelligence Brief. https://druglandscape.com/ci/gabapentin-enacarbil. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing