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full-dose olanzapine — Competitive Intelligence Brief
marketed
Atypical antipsychotic
Dopamine D2 receptor, Serotonin 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
full-dose olanzapine (full-dose olanzapine) — Kaohsiung Kai-Suan Psychiatric Hospital. Olanzapine is an atypical antipsychotic that blocks dopamine D2 and serotonin 5-HT2A receptors in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| full-dose olanzapine TARGET | full-dose olanzapine | Kaohsiung Kai-Suan Psychiatric Hospital | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| sodium valproate with Clozapine | sodium valproate with Clozapine | Shanghai Mental Health Center | marketed | Antipsychotic + mood stabilizer combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase | |
| paliperidone clozapine | paliperidone clozapine | Universidad Nacional de Rosario | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Fluoxetine+Olanzapine | Fluoxetine+Olanzapine | University Health Network, Toronto | marketed | SSRI + atypical antipsychotic combination | Serotonin transporter (SERT), dopamine D2 receptor, serotonin 5-HT2A receptor | |
| Olanzapine-Fluoxetine Combination | Olanzapine-Fluoxetine Combination | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| risperidone (Risperdal) | risperidone (Risperdal) | University of South Florida | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| quetiapine (Seroquel) XR | quetiapine (Seroquel) XR | Dr. D McIntosh & Dr. K Kjernisted Clinical Research Inc. | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). full-dose olanzapine — Competitive Intelligence Brief. https://druglandscape.com/ci/full-dose-olanzapine. Accessed 2026-06-10.
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