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Last reviewed 2026-05-17 · How we verify

fosnetupitant/ palonosetron — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

fosnetupitant/ palonosetron (fosnetupitant/ palonosetron) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NK1 receptor antagonist / 5-HT3 receptor antagonist combination. Area: Oncology.

marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (substance P receptor) / 5-HT3 receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

fosnetupitant/ palonosetron (fosnetupitant/ palonosetron) — Helsinn Healthcare SA. Fosnetupitant is an NK1 receptor antagonist and palonosetron is a 5-HT3 receptor antagonist that together prevent chemotherapy-induced nausea and vomiting (CINV) by blocking two distinct pathways in the chemoreceptor trigger zone and gastrointestinal tract.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
fosnetupitant/ palonosetron TARGET	fosnetupitant/ palonosetron	Helsinn Healthcare SA	marketed	NK1 receptor antagonist / 5-HT3 receptor antagonist combination	NK1 receptor (substance P receptor) / 5-HT3 receptor
Akynzeo solution	Akynzeo solution	Helsinn Healthcare SA	marketed	NK1 receptor antagonist / 5-HT3 receptor antagonist combination	NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NK1 receptor antagonist / 5-HT3 receptor antagonist combination class)

Helsinn Healthcare SA · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). fosnetupitant/ palonosetron — Competitive Intelligence Brief. https://druglandscape.com/ci/fosnetupitant-palonosetron. Accessed 2026-05-17.

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