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FOLFOXIRI with bevacizumab — Competitive Intelligence Brief
phase 3
Chemotherapy combination with anti-angiogenic monoclonal antibody
VEGF (bevacizumab component); topoisomerase I, thymidylate synthase, DNA (FOLFOXIRI components)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
FOLFOXIRI with bevacizumab (FOLFOXIRI with bevacizumab) — Dutch Colorectal Cancer Group. FOLFOXIRI with bevacizumab combines three chemotherapy drugs (fluorouracil, oxaliplatin, and irinotecan) with an anti-angiogenic monoclonal antibody to kill colorectal cancer cells and block tumor blood vessel formation.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| FOLFOXIRI with bevacizumab TARGET | FOLFOXIRI with bevacizumab | Dutch Colorectal Cancer Group | phase 3 | Chemotherapy combination with anti-angiogenic monoclonal antibody | VEGF (bevacizumab component); topoisomerase I, thymidylate synthase, DNA (FOLFOXIRI components) | |
| FOLFOX/ FOLFIRI with bevacizumab | FOLFOX/ FOLFIRI with bevacizumab | Dutch Colorectal Cancer Group | phase 3 | Chemotherapy combination with anti-angiogenic monoclonal antibody | DNA (chemotherapy); VEGF (bevacizumab) | |
| Placebo+cisplatin/carboplatin+paclitaxel+Bevacizumab | Placebo+cisplatin/carboplatin+paclitaxel+Bevacizumab | Lee's Pharmaceutical Limited | phase 3 | Chemotherapy combination with anti-angiogenic monoclonal antibody | DNA (platinum agents), microtubules (paclitaxel), VEGF (bevacizumab) | |
| carboplatin paclitaxel bevacizumab | carboplatin paclitaxel bevacizumab | Gruppo Oncologico Italia Meridionale | phase 3 | Chemotherapy combination with anti-angiogenic monoclonal antibody | DNA (carboplatin), microtubules (paclitaxel), VEGF (bevacizumab) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination with anti-angiogenic monoclonal antibody class)
- Dutch Colorectal Cancer Group · 2 drugs in this class
- Gruppo Oncologico Italia Meridionale · 1 drug in this class
- Lee's Pharmaceutical Limited · 1 drug in this class
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Cite this brief
Drug Landscape (2026). FOLFOXIRI with bevacizumab — Competitive Intelligence Brief. https://druglandscape.com/ci/folfoxiri-with-bevacizumab. Accessed 2026-05-16.
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