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FOLFOX/ FOLFIRI with bevacizumab — Competitive Intelligence Brief

FOLFOX/ FOLFIRI with bevacizumab (FOLFOX/ FOLFIRI with bevacizumab) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Chemotherapy combination with anti-angiogenic monoclonal antibody. Area: Oncology.

phase 3 Chemotherapy combination with anti-angiogenic monoclonal antibody DNA (chemotherapy); VEGF (bevacizumab) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FOLFOX/ FOLFIRI with bevacizumab (FOLFOX/ FOLFIRI with bevacizumab) — Dutch Colorectal Cancer Group. FOLFOX/FOLFIRI chemotherapy regimens combined with bevacizumab inhibit tumor cell division and block new blood vessel formation to starve tumors of nutrients.

Comparator set (3 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
FOLFOX/ FOLFIRI with bevacizumab TARGET FOLFOX/ FOLFIRI with bevacizumab Dutch Colorectal Cancer Group phase 3 Chemotherapy combination with anti-angiogenic monoclonal antibody DNA (chemotherapy); VEGF (bevacizumab)
Placebo+cisplatin/carboplatin+paclitaxel+Bevacizumab Placebo+cisplatin/carboplatin+paclitaxel+Bevacizumab Lee's Pharmaceutical Limited phase 3 Chemotherapy combination with anti-angiogenic monoclonal antibody DNA (platinum agents), microtubules (paclitaxel), VEGF (bevacizumab)
FOLFOXIRI with bevacizumab FOLFOXIRI with bevacizumab Dutch Colorectal Cancer Group phase 3 Chemotherapy combination with anti-angiogenic monoclonal antibody VEGF (bevacizumab component); topoisomerase I, thymidylate synthase, DNA (FOLFOXIRI components)
carboplatin paclitaxel bevacizumab carboplatin paclitaxel bevacizumab Gruppo Oncologico Italia Meridionale phase 3 Chemotherapy combination with anti-angiogenic monoclonal antibody DNA (carboplatin), microtubules (paclitaxel), VEGF (bevacizumab)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Chemotherapy combination with anti-angiogenic monoclonal antibody class)

  1. Dutch Colorectal Cancer Group · 2 drugs in this class
  2. Gruppo Oncologico Italia Meridionale · 1 drug in this class
  3. Lee's Pharmaceutical Limited · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FOLFOX/ FOLFIRI with bevacizumab — Competitive Intelligence Brief. https://druglandscape.com/ci/folfox-folfiri-with-bevacizumab. Accessed 2026-05-17.

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