Who are FOLFOX 1d's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): CEV chemotherapy, Consolidation Chemotherapy, Carboplatin, Etoposide, Ifosfamide, Dexamethasona, Idarubicine, ARA-C, Methotrexate, PTH followed by dose dense AC of FEC, CVP.

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Last reviewed 2026-05-13 · How we verify

FOLFOX 1d — Competitive Intelligence Brief

FOLFOX 1d (FOLFOX 1d) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Thymidylate synthase (5-FU); DNA (oxaliplatin) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FOLFOX 1d (FOLFOX 1d) — Sun Yat-sen University. FOLFOX 1d is a chemotherapy regimen combining 5-fluorouracil, leucovorin, and oxaliplatin to inhibit DNA synthesis and induce apoptosis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
FOLFOX 1d TARGET	FOLFOX 1d	Sun Yat-sen University	phase 3	Combination chemotherapy regimen	Thymidylate synthase (5-FU); DNA (oxaliplatin)
CEV chemotherapy	CEV chemotherapy	Sun Yat-sen University	marketed	Combination chemotherapy regimen
Consolidation Chemotherapy	Consolidation Chemotherapy	National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos	marketed	Combination chemotherapy regimen
Carboplatin, Etoposide, Ifosfamide	Carboplatin, Etoposide, Ifosfamide	University Hospital Muenster	marketed	Combination chemotherapy regimen	DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)
Dexamethasona, Idarubicine, ARA-C, Methotrexate	Dexamethasona, Idarubicine, ARA-C, Methotrexate	PETHEMA Foundation	marketed	Combination chemotherapy regimen
PTH followed by dose dense AC of FEC	PTH followed by dose dense AC of FEC	Agendia	marketed	Combination chemotherapy regimen with monoclonal antibody	HER2 receptor; microtubule; DNA (topoisomerase II)
CVP	CVP	SCRI Development Innovations, LLC	marketed	Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

Sun Yat-sen University · 5 drugs in this class
Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
Hoffmann-La Roche · 2 drugs in this class
University Hospital, Bordeaux · 2 drugs in this class
Beijing Friendship Hospital · 1 drug in this class
Centre Hospitalier Universitaire Dijon · 1 drug in this class
Amgen · 1 drug in this class
Chungnam National University Hospital · 1 drug in this class
AstraZeneca · 1 drug in this class
Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FOLFOX 1d — Competitive Intelligence Brief. https://druglandscape.com/ci/folfox-1d. Accessed 2026-05-13.

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