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FOLFIRI + cetuximab — Competitive Intelligence Brief
marketed
Chemotherapy combination + monoclonal antibody
EGFR (epidermal growth factor receptor); DNA (via FOLFIRI)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
FOLFIRI + cetuximab (FOLFIRI + cetuximab) — Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD). FOLFIRI chemotherapy combined with cetuximab targets rapidly dividing cancer cells and blocks epidermal growth factor receptor (EGFR) signaling to inhibit tumor growth.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| FOLFIRI + cetuximab TARGET | FOLFIRI + cetuximab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | marketed | Chemotherapy combination + monoclonal antibody | EGFR (epidermal growth factor receptor); DNA (via FOLFIRI) | |
| FOLFOXIRI + Bevacizumab | FOLFOXIRI + Bevacizumab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | phase 3 | Chemotherapy combination + monoclonal antibody (anti-VEGF) | DNA (chemotherapy); VEGF (bevacizumab) | |
| modified FOLFOX6 + bevacizumab | modified FOLFOX6 + bevacizumab | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | phase 3 | Chemotherapy combination + monoclonal antibody | DNA (chemotherapy); VEGF (bevacizumab) | |
| Folfox with avastin | Folfox with avastin | Sherief Abd-Elsalam | phase 3 | Chemotherapy combination + monoclonal antibody (anti-VEGF) | DNA (chemotherapy); VEGF (bevacizumab) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination + monoclonal antibody class)
- Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). FOLFIRI + cetuximab — Competitive Intelligence Brief. https://druglandscape.com/ci/folfiri-cetuximab. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing