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Flupentixole — Competitive Intelligence Brief
marketed
Antipsychotic
Dopamine D2 receptors
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Flupentixole (Flupentixole) — Technical University of Munich. Flupentixole is a dopamine D2 receptor antagonist that reduces psychotic symptoms by blocking dopamine receptors in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Flupentixole TARGET | Flupentixole | Technical University of Munich | marketed | Antipsychotic | Dopamine D2 receptors | |
| Crushed ticagrelor, morphine,metoclopramide | Crushed ticagrelor, morphine,metoclopramide | Collegium Medicum w Bydgoszczy | marketed | Antiplatelet agent + opioid analgesic + antiemetic (combination therapy) | P2Y12 receptor (ticagrelor); mu opioid receptors (morphine); dopamine D2 receptors (metoclopramide) | |
| Quetiapine 600mg | Quetiapine 600mg | AstraZeneca | marketed | atypical antipsychotic | ["serotonin 5-HT2A receptors", "dopamine D2 receptors"] | |
| SAMIDORPHAN L-MALATE | SAMIDORPHAN L-MALATE | marketed | Atypical Antipsychotic [EPC] | dopamine and serotonin type 2 (5HT2) receptors, opioid receptors | 2021-01-01 | |
| Lybalvi | SAMIDORPHAN | Alkermes Inc | marketed | Atypical Antipsychotic [EPC] | Mu-type opioid receptor | 2021-01-01 |
| Caplyta | LUMATEPERONE | Intra-Cellular | marketed | Atypical Antipsychotic [EPC] | 5-hydroxytryptamine receptor 2A | 2019-01-01 |
| Nuplazid | PIMAVANSERIN | Acadia Pharms Inc | marketed | Atypical Antipsychotic | 5-hydroxytryptamine receptor 2A | 2016-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Lybalvi · 11351166 · US
- — Lybalvi · 11241425 · US
- — Lybalvi · 9126977 · US
- — Lybalvi · 10300054 · US
- — Lybalvi · 10716785 · US
- — Lybalvi · 11185541 · US
- — Lybalvi · 9517235 · US
- — Lybalvi · 9119848 · US
- — Lybalvi · 8778960 · US
Sponsor landscape (Antipsychotic class)
- Fundación Pública Andaluza Progreso y Salud · 1 drug in this class
- Ludwig-Maximilians - University of Munich · 1 drug in this class
- Technical University of Munich · 1 drug in this class
- University of Utah · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Flupentixole — Competitive Intelligence Brief. https://druglandscape.com/ci/flupentixole. Accessed 2026-05-13.
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