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FLOT — Competitive Intelligence Brief

FLOT (FLOT) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Chemotherapy regimen (combination). Area: Oncology.

marketed Chemotherapy regimen (combination) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FLOT (FLOT) — European Organisation for Research and Treatment of Cancer - EORTC. FLOT is a chemotherapy regimen combining fluorouracil, leucovorin, oxaliplatin, and docetaxel to inhibit DNA synthesis and microtubule formation, killing rapidly dividing cancer cells.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
FLOT TARGET FLOT European Organisation for Research and Treatment of Cancer - EORTC marketed Chemotherapy regimen (combination)
TCH chemotherapy TCH chemotherapy Agendia marketed Chemotherapy regimen (combination) HER2, microtubule, DNA
TAC chemotherapy TAC chemotherapy Agendia marketed Chemotherapy regimen (combination)
AC-P,TEC,AC,TC,TCH,CEF,TAC,CAF AC-P,TEC,AC,TC,TCH,CEF,TAC,CAF Shandong Cancer Hospital and Institute phase 3 Chemotherapy regimen (combination)
C-BEAM Regimen C-BEAM Regimen The First Affiliated Hospital with Nanjing Medical University phase 3 Chemotherapy regimen (combination)
dtEC→dtT dtEC→dtT Karolinska University Hospital phase 3 Chemotherapy regimen (combination)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Chemotherapy regimen (combination) class)

  1. Agendia · 2 drugs in this class
  2. European Organisation for Research and Treatment of Cancer - EORTC · 1 drug in this class
  3. Karolinska University Hospital · 1 drug in this class
  4. Shandong Cancer Hospital and Institute · 1 drug in this class
  5. The First Affiliated Hospital with Nanjing Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FLOT — Competitive Intelligence Brief. https://druglandscape.com/ci/flot. Accessed 2026-05-14.

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