Who are FLOLAN injection with reformulated diluent's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Epalrestat,Mecobalamin, Inhaled Epoprostenol and phenylephrine, Ventavis (Iloprost, BAYQ6256), Iloprost Injection, for intravenous use, LIQ861 Inhaled Treprostinil, iloprost (5 µg).

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Last reviewed 2026-05-16 · How we verify

FLOLAN injection with reformulated diluent — Competitive Intelligence Brief

FLOLAN injection with reformulated diluent (FLOLAN injection with reformulated diluent) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Prostacyclin analog. Area: Cardiovascular.

marketed Prostacyclin analog Prostacyclin receptor (IP receptor) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

FLOLAN injection with reformulated diluent (FLOLAN injection with reformulated diluent) — GlaxoSmithKline. Epoprostenol (prostacyclin) directly relaxes vascular smooth muscle and inhibits platelet aggregation to reduce pulmonary vascular resistance.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
FLOLAN injection with reformulated diluent TARGET	FLOLAN injection with reformulated diluent	GlaxoSmithKline	marketed	Prostacyclin analog	Prostacyclin receptor (IP receptor)
Epalrestat,Mecobalamin	Epalrestat,Mecobalamin	Xiangya Hospital of Central South University	marketed	Prostacyclin analog + Cobalamin derivative combination	Prostacyclin receptor (IP receptor) + Methylcobalamin-dependent enzymes
Inhaled Epoprostenol and phenylephrine	Inhaled Epoprostenol and phenylephrine	University Health Network, Toronto	marketed	Prostacyclin analog with alpha-1 adrenergic agonist	Prostacyclin receptor (IP receptor); alpha-1 adrenergic receptor
Ventavis (Iloprost, BAYQ6256)	Ventavis (Iloprost, BAYQ6256)	Bayer	phase 3	Prostacyclin analogue	Prostacyclin receptor
Iloprost Injection, for intravenous use	Iloprost Injection, for intravenous use	Civi Biopharma, Inc.	phase 3	Prostacyclin analog	Prostacyclin receptor (IP receptor)
LIQ861 Inhaled Treprostinil	LIQ861 Inhaled Treprostinil	Liquidia Technologies, Inc.	phase 3	Prostacyclin analog	Prostacyclin receptor (IP receptor)
iloprost (5 µg)	iloprost (5 µg)	Actelion	phase 3	prostacyclin analogue	prostacyclin receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Prostacyclin analog class)

Liquidia Technologies, Inc. · 2 drugs in this class
AOP Orphan Pharmaceuticals AG · 1 drug in this class
Civi Biopharma, Inc. · 1 drug in this class
GlaxoSmithKline · 1 drug in this class
Ludwig-Maximilians - University of Munich · 1 drug in this class
Lung Biotechnology PBC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FLOLAN injection with reformulated diluent — Competitive Intelligence Brief. https://druglandscape.com/ci/flolan-injection-with-reformulated-diluent. Accessed 2026-05-16.

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