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Extract of Agaricus blazei Murill — Competitive Intelligence Brief
phase 3
Immunomodulator; natural product extract
Pattern recognition receptors (Dectin-1, TLR); macrophage and NK cell activation
Oncology; Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Extract of Agaricus blazei Murill (Extract of Agaricus blazei Murill) — ECbiotech Taiwan. Agaricus blazei Murill extract enhances immune function through polysaccharide and beta-glucan components that activate macrophages, natural killer cells, and other innate immune cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Extract of Agaricus blazei Murill TARGET | Extract of Agaricus blazei Murill | ECbiotech Taiwan | phase 3 | Immunomodulator; natural product extract | Pattern recognition receptors (Dectin-1, TLR); macrophage and NK cell activation | |
| histamine dihydrochloride and IL-2 | histamine dihydrochloride and IL-2 | Cytovia, Inc. | marketed | Immunomodulator combination | Histamine receptors (H1, H2, H3, H4) and IL-2 receptor | |
| Single Dose of Hydroxychloroquine | Single Dose of Hydroxychloroquine | Shahid Beheshti University of Medical Sciences | marketed | Antimalarial immunomodulator | Toll-like receptors (TLR); lysosomal pH modulation | |
| BG00012 (DMF) | BG00012 (DMF) | Biogen | marketed | Fumaric acid ester; immunomodulator | Nrf2 (nuclear factor erythroid 2-related factor 2) | |
| Interferon-Alpha | Interferon-Alpha | University of Birmingham | marketed | Cytokine; Immunomodulator | Interferon-alpha receptor (IFNAR) | |
| PAD combination | PAD combination | Cooperative Study Group A for Hematology | marketed | Combination therapy (proteasome inhibitor + immunomodulatory agent + corticosteroid) | 26S proteasome; cereblon (CRBN); glucocorticoid receptor | |
| Iguratimod Tablets | Iguratimod Tablets | Wangjing Hospital, China Academy of Chinese Medical Sciences | marketed | Small-molecule immunomodulator | NF-κB pathway; multiple cytokine targets |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Immunomodulator; natural product extract class)
- ECbiotech Taiwan · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Extract of Agaricus blazei Murill — Competitive Intelligence Brief. https://druglandscape.com/ci/extract-of-agaricus-blazei-murill. Accessed 2026-05-17.
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