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Extract of Agaricus blazei Murill — Competitive Intelligence Brief

Extract of Agaricus blazei Murill (Extract of Agaricus blazei Murill) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Immunomodulator; natural product extract. Area: Oncology; Immunology.

phase 3 Immunomodulator; natural product extract Pattern recognition receptors (Dectin-1, TLR); macrophage and NK cell activation Oncology; Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Extract of Agaricus blazei Murill (Extract of Agaricus blazei Murill) — ECbiotech Taiwan. Agaricus blazei Murill extract enhances immune function through polysaccharide and beta-glucan components that activate macrophages, natural killer cells, and other innate immune cells.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Extract of Agaricus blazei Murill TARGET Extract of Agaricus blazei Murill ECbiotech Taiwan phase 3 Immunomodulator; natural product extract Pattern recognition receptors (Dectin-1, TLR); macrophage and NK cell activation
histamine dihydrochloride and IL-2 histamine dihydrochloride and IL-2 Cytovia, Inc. marketed Immunomodulator combination Histamine receptors (H1, H2, H3, H4) and IL-2 receptor
Single Dose of Hydroxychloroquine Single Dose of Hydroxychloroquine Shahid Beheshti University of Medical Sciences marketed Antimalarial immunomodulator Toll-like receptors (TLR); lysosomal pH modulation
BG00012 (DMF) BG00012 (DMF) Biogen marketed Fumaric acid ester; immunomodulator Nrf2 (nuclear factor erythroid 2-related factor 2)
Interferon-Alpha Interferon-Alpha University of Birmingham marketed Cytokine; Immunomodulator Interferon-alpha receptor (IFNAR)
PAD combination PAD combination Cooperative Study Group A for Hematology marketed Combination therapy (proteasome inhibitor + immunomodulatory agent + corticosteroid) 26S proteasome; cereblon (CRBN); glucocorticoid receptor
Iguratimod Tablets Iguratimod Tablets Wangjing Hospital, China Academy of Chinese Medical Sciences marketed Small-molecule immunomodulator NF-κB pathway; multiple cytokine targets

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Immunomodulator; natural product extract class)

  1. ECbiotech Taiwan · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Extract of Agaricus blazei Murill — Competitive Intelligence Brief. https://druglandscape.com/ci/extract-of-agaricus-blazei-murill. Accessed 2026-05-17.

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