Who are Experimental drug: Aprepitant's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): fosnetupitant/ palonosetron, Akynzeo solution, Aprepitant plus Ondansetron, Fosaprepitant for Injection, Standard: Aprepitant, OPC-61815 injection.

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Last reviewed 2026-05-16 · How we verify

Experimental drug: Aprepitant — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Experimental drug: Aprepitant (Experimental drug: Aprepitant) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NK1 receptor antagonist. Area: Oncology / Supportive Care.

phase 3 NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor) Oncology / Supportive Care Small molecule Live · refreshed every 30 min

Target snapshot

Experimental drug: Aprepitant (Experimental drug: Aprepitant) — CCTU. Aprepitant blocks neurokinin-1 (NK1) receptors in the brain to prevent nausea and vomiting.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Experimental drug: Aprepitant TARGET	Experimental drug: Aprepitant	CCTU	phase 3	NK1 receptor antagonist	NK1 receptor (neurokinin-1 receptor)
fosnetupitant/ palonosetron	fosnetupitant/ palonosetron	Helsinn Healthcare SA	marketed	NK1 receptor antagonist / 5-HT3 receptor antagonist combination	NK1 receptor (substance P receptor) / 5-HT3 receptor
Akynzeo solution	Akynzeo solution	Helsinn Healthcare SA	marketed	NK1 receptor antagonist / 5-HT3 receptor antagonist combination	NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component)
Aprepitant plus Ondansetron	Aprepitant plus Ondansetron	University of Pittsburgh	marketed	NK1 receptor antagonist + 5-HT3 receptor antagonist combination	NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron)
Fosaprepitant for Injection	Fosaprepitant for Injection	Montefiore Medical Center	marketed	NK1 receptor antagonist	NK1 receptor (neurokinin-1 receptor)
Standard: Aprepitant	Standard: Aprepitant	CCTU	phase 3	NK1 receptor antagonist	NK1 receptor
OPC-61815 injection	OPC-61815 injection	Otsuka Pharmaceutical Co., Ltd.	phase 3	NK1 receptor antagonist	NK1 receptor (neurokinin-1 receptor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NK1 receptor antagonist class)

Merck Sharp & Dohme LLC · 4 drugs in this class
GlaxoSmithKline · 3 drugs in this class
Organon and Co · 3 drugs in this class
CCTU · 2 drugs in this class
Acacia Pharma Ltd · 2 drugs in this class
Sanofi · 1 drug in this class
Santen SAS · 1 drug in this class
CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
Montefiore Medical Center · 1 drug in this class
New Mexico Cancer Research Alliance · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Experimental drug: Aprepitant — Competitive Intelligence Brief. https://druglandscape.com/ci/experimental-drug-aprepitant. Accessed 2026-05-16.

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