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exenatide and sitagliptin — Competitive Intelligence Brief
marketed
GLP-1 receptor agonist and DPP-4 inhibitor combination
GLP-1 receptor (exenatide); DPP-4 (sitagliptin)
Diabetes
Small molecule
Live · refreshed every 30 min
Target snapshot
exenatide and sitagliptin (exenatide and sitagliptin) — AstraZeneca. This combination drug stimulates insulin secretion through two complementary pathways: exenatide activates GLP-1 receptors to enhance glucose-dependent insulin release, while sitagliptin inhibits DPP-4 to prolong the action of endogenous GLP-1 and GIP.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| exenatide and sitagliptin TARGET | exenatide and sitagliptin | AstraZeneca | marketed | GLP-1 receptor agonist and DPP-4 inhibitor combination | GLP-1 receptor (exenatide); DPP-4 (sitagliptin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GLP-1 receptor agonist and DPP-4 inhibitor combination class)
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). exenatide and sitagliptin — Competitive Intelligence Brief. https://druglandscape.com/ci/exenatide-and-sitagliptin. Accessed 2026-05-16.
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