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Trombarin — Competitive Intelligence Brief
phase 2
ethyl biscoumacetate
Vitamin K epoxide reductase complex subunit 1
Hematology
Small molecule
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Target snapshot
Trombarin (ETHYL BISCOUMACETATE). Trombarin works by inhibiting the enzyme Vitamin K epoxide reductase complex subunit 1, which is involved in the recycling of vitamin K.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Trombarin TARGET | ETHYL BISCOUMACETATE | phase 2 | ethyl biscoumacetate | Vitamin K epoxide reductase complex subunit 1 | ||
| PHYTONADIONE | PHYTONADIONE | marketed | Vitamin K [EPC] | Vitamin K epoxide reductase complex subunit 1 (VKORC1) | 1982-01-01 | |
| Indion | PHENINDIONE | Sanofi | marketed | phenindione | Prothrombin, Vitamin K epoxide reductase complex subunit 1, Arachidonate 5-lipoxygenase | 1982-01-01 |
| Coumadin | warfarin | Generic (originally Wisconsin Alumni Research Foundation) | marketed | Vitamin K antagonist (anticoagulant) | Vitamin K epoxide reductase complex subunit 1-like protein 1, Cytochrome P450 2C9, Proprotein convertase subtilisin/kexin type 7 | 1954-01-01 |
| Sintrom | ACENOCOUMAROL | phase 3 | acenocoumarol | Vitamin K epoxide reductase complex subunit 1 |
Recent regulatory actions (last 90 days)
- — PHYTONADIONE · FDA · approved · US
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (ethyl biscoumacetate class)
- · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Trombarin — Competitive Intelligence Brief. https://druglandscape.com/ci/ethyl-biscoumacetate. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing