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Etavopivat tablets — Competitive Intelligence Brief
phase 3
Protein kinase C (PKC) activator
PKC (Protein Kinase C)
Hematology/Rare Blood Disorders
Small molecule
Live · refreshed every 30 min
Target snapshot
Etavopivat tablets (Etavopivat tablets) — Forma Therapeutics, Inc.. Etavopivat activates the protein kinase PKC (protein kinase C) to increase fetal hemoglobin (HbF) production, thereby reducing sickling and hemolysis in red blood cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Etavopivat tablets TARGET | Etavopivat tablets | Forma Therapeutics, Inc. | phase 3 | Protein kinase C (PKC) activator | PKC (Protein Kinase C) | |
| ingenol mebutate 0.015% | ingenol mebutate 0.015% | Icahn School of Medicine at Mount Sinai | marketed | Protein kinase C (PKC) activator | Protein kinase C (PKC) | |
| Ingenol Mebutate (Reference) | Ingenol Mebutate (Reference) | Padagis LLC | phase 3 | Protein kinase C (PKC) activator | Protein kinase C (PKC) | |
| Ingenol Mebutate (Perrigo) | Ingenol Mebutate (Perrigo) | Padagis LLC | phase 3 | Protein kinase C (PKC) activator | Protein kinase C (PKC) | |
| Ingenol Mebutate (Picato®) | Ingenol Mebutate (Picato®) | Actavis Inc. | phase 3 | Protein kinase C (PKC) activator | Protein kinase C (PKC) | |
| PEP005 (ingenol mebutate) Gel | PEP005 (ingenol mebutate) Gel | Peplin | phase 3 | Protein kinase C (PKC) activator | Protein kinase C (PKC) | |
| Ingenol metabute | Ingenol metabute | LEO Pharma | phase 3 | Protein kinase C (PKC) activator | Protein kinase C (PKC) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Protein kinase C (PKC) activator class)
- Padagis LLC · 2 drugs in this class
- Actavis Inc. · 1 drug in this class
- Forma Therapeutics, Inc. · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- LEO Pharma · 1 drug in this class
- Peplin · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Etavopivat tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/etavopivat-tablets. Accessed 2026-06-10.
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