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Etavopivat A — Competitive Intelligence Brief
phase 3
Nrf2 activator
Nrf2 (NFE2L2)
Hematology/Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Etavopivat A (Etavopivat A) — Novo Nordisk A/S. Etavopivat activates the Nrf2 (nuclear factor erythroid 2-related factor 2) pathway to increase fetal hemoglobin (HbF) production and reduce hemolysis in patients with sickle cell disease.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Etavopivat A TARGET | Etavopivat A | Novo Nordisk A/S | phase 3 | Nrf2 activator | Nrf2 (NFE2L2) | |
| BG00012 (DMF) (Tecfidera®.) | BG00012 (DMF) (Tecfidera®.) | Multiple Sclerosis Center of Northeastern New York | marketed | Fumaric acid ester; Nrf2 activator | Nuclear factor erythroid 2-related factor 2 (Nrf2) | |
| Etavopivat Tablets High dose | Etavopivat Tablets High dose | Forma Therapeutics, Inc. | phase 3 | Nrf2 activator | Nrf2 (NFE2L2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nrf2 activator class)
- Forma Therapeutics, Inc. · 1 drug in this class
- Novo Nordisk A/S · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Etavopivat A — Competitive Intelligence Brief. https://druglandscape.com/ci/etavopivat-a. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing