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Eszopiclone (Lunesta) — Competitive Intelligence Brief
marketed
Nonbenzodiazepine hypnotic (Z-drug)
GABA-A receptor (alpha-1 subunit)
Neurology / Sleep Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
Eszopiclone (Lunesta) (Eszopiclone (Lunesta)) — Sumitomo Pharma America, Inc.. Eszopiclone is a nonbenzodiazepine hypnotic that binds to GABA-A receptors in the brain to promote sleep onset and maintenance.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Eszopiclone (Lunesta) TARGET | Eszopiclone (Lunesta) | Sumitomo Pharma America, Inc. | marketed | Nonbenzodiazepine hypnotic (Z-drug) | GABA-A receptor (alpha-1 subunit) | |
| Eszopiclone 1 mg- Elderly | Eszopiclone 1 mg- Elderly | Eisai Co., Ltd. | phase 3 | Nonbenzodiazepine hypnotic (Z-drug) | GABA-A receptor | |
| Eszopiclone 3 mg- Non-elderly | Eszopiclone 3 mg- Non-elderly | Eisai Co., Ltd. | phase 3 | Nonbenzodiazepine hypnotic (Z-drug) | GABA-A receptor | |
| Eszopiclone 2 mg- Non-elderly | Eszopiclone 2 mg- Non-elderly | Eisai Co., Ltd. | phase 3 | Nonbenzodiazepine hypnotic (Z-drug) | GABA-A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nonbenzodiazepine hypnotic (Z-drug) class)
- Eisai Co., Ltd. · 3 drugs in this class
- Sumitomo Pharma America, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Eszopiclone (Lunesta) — Competitive Intelligence Brief. https://druglandscape.com/ci/eszopiclone-lunesta. Accessed 2026-05-18.
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