Who are Benzofoline's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Inluriyo, Orserdu, Nextstellis, Annovera, Duavee, Duavee.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/estradiol-benzoate.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Benzofoline — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Benzofoline (ESTRADIOL BENZOATE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Estrogen. Area: Nephrology.

marketed Estrogen Adenosine receptor A3, Sex hormone-binding globulin, 5-hydroxytryptamine receptor 2B Nephrology Small molecule Live · refreshed every 30 min

Target snapshot

Benzofoline (ESTRADIOL BENZOATE).

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Benzofoline TARGET	ESTRADIOL BENZOATE		marketed	Estrogen	Adenosine receptor A3, Sex hormone-binding globulin, 5-hydroxytryptamine receptor 2B
Inluriyo	IMLUNESTRANT	Eli Lilly And Co	marketed	Estrogen Receptor Antagonist [EPC]		2025-01-01
Orserdu	ELACESTRANT	Stemline Therap	marketed	Estrogen Receptor Antagonist [EPC]	Estrogen receptor	2023-01-01
Nextstellis	ESTETROL	Mayne Pharma	marketed	Estrogen	Estrogen receptor	2021-01-01
Annovera	SEGESTERONE	Mayne Pharma	marketed	Estrogen [EPC]		2018-01-01
Duavee	BAZEDOXIFENE	Wyeth Pharms Pfizer	marketed	Estrogen [EPC]	estrogen receptors (ER) α and β	2013-01-01
Duavee	conjugated-estrogens-bazedoxifene	Pfizer	marketed	Estrogen [EPC]	estrogen receptors α and β	2013-01-01

Recent regulatory actions (last 90 days)

2026-03-26 — Nextstellis · EMA · approved · EU · Mayne Pharma

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2027-03-10 — Duavee · 7683051 · US

Sponsor landscape (Estrogen class)

· 7 drugs in this class
Pfizer · 2 drugs in this class
Mayne Pharma · 1 drug in this class
Pfizer Inc. · 1 drug in this class
Ph Health · 1 drug in this class
Merck & Co. · 1 drug in this class
Apil · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Benzofoline — Competitive Intelligence Brief. https://druglandscape.com/ci/estradiol-benzoate. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing