Who are Femring's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Duavee, Duavee, Evista, Premarin, Premarin, Premarin.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/estradiol-acetate.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-14 · How we verify

Femring — Competitive Intelligence Brief

Femring (ESTRADIOL ACETATE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Estrogen. Area: Metabolic.

marketed Estrogen estrogen receptors Metabolic Small molecule Live · refreshed every 30 min

Target snapshot

Femring (ESTRADIOL ACETATE) — Apil. Estrogens, primarily estradiol, bind to nuclear receptors in estrogen-responsive tissues, modulating the female reproductive system and reducing postmenopausal gonadotropin levels.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Femring TARGET	ESTRADIOL ACETATE	Apil	marketed	Estrogen	estrogen receptors	2003-01-01
Duavee	conjugated-estrogens-bazedoxifene	Pfizer	marketed	Estrogen [EPC]	estrogen receptors α and β	2013-01-01
Duavee	BAZEDOXIFENE	Wyeth Pharms Pfizer	marketed	Estrogen [EPC]	estrogen receptors (ER) α and β	2013-01-01
Evista	RALOXIFENE	Eli Lilly	marketed	Estrogen Agonist/Antagonist	estrogen receptors	1997-01-01
Premarin	Estrogens, Conjugated	Pfizer	marketed	Estrogen replacement therapy	Estrogen receptors (nuclear receptors)	1942-01-01
Premarin	Estrogens, Conjugated	Pfizer	marketed	Estrogen replacement therapy	Estrogen receptors (nuclear receptors)	1942-01-01
Premarin	Estrogens, Conjugated	Pfizer	marketed	Estrogen replacement therapy	Estrogen receptors (nuclear receptors)	1942-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2027-03-10 — Duavee · 7683051 · US
2028-07-10 — Femring · 9730900 · Method of Use · US
2028-07-10 — Femring · 9724310 · Compound · US
2028-07-10 — Femring · 9833419 · Formulation · US
2030-07-04 — Femring · 8231906 · Compound · US
2032-11-21 — Femring · 10537581 · Formulation · US
2032-11-21 — Femring · 11246875 · Method of Use · US
2032-11-21 — Femring · 11241445 · Method of Use · US
2032-11-21 — Femring · 10668082 · Method of Use · US
2032-11-21 — Femring · 10568891 · Method of Use · US
2032-11-21 — Femring · 9180091 · Formulation · US
2032-11-21 — Femring · 11497709 · Method of Use · US
2032-11-21 — Femring · 10835487 · Method of Use · US
2032-11-21 — Femring · 10888516 · Method of Use · US
2032-11-21 — Femring · 11351182 · Method of Use · US
2032-11-21 — Femring · 11116717 · Formulation · US
2032-11-21 — Femring · 11065197 · Formulation · US
2032-11-21 — Femring · 10258630 · Method of Use · US
2032-11-21 — Femring · 11123283 · Formulation · US
2032-11-21 — Femring · 9289382 · Formulation · US
2032-11-21 — Femring · 10806697 · Formulation · US
2032-11-21 — Femring · 10398708 · Method of Use · US
2032-11-21 — Femring · 10471072 · Method of Use · US
2032-11-21 — Femring · 11304959 · Formulation · US
2034-02-02 — Femring · 11266661 · Method of Use · US

Sponsor landscape (Estrogen class)

· 7 drugs in this class
Pfizer · 2 drugs in this class
Mayne Pharma · 1 drug in this class
Pfizer Inc. · 1 drug in this class
Ph Health · 1 drug in this class
Merck & Co. · 1 drug in this class
Apil · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Femring — Competitive Intelligence Brief. https://druglandscape.com/ci/estradiol-acetate. Accessed 2026-05-14.

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