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Escitalopram + Bupropion SR — Competitive Intelligence Brief

Escitalopram + Bupropion SR (Escitalopram + Bupropion SR) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: SSRI + NDRI combination. Area: Psychiatry / Mental Health.

marketed SSRI + NDRI combination Serotonin transporter (SERT); Norepinephrine transporter (NET); Dopamine transporter (DAT) Psychiatry / Mental Health Small molecule Live · refreshed every 30 min

Target snapshot

Escitalopram + Bupropion SR (Escitalopram + Bupropion SR) — National Institute of Mental Health (NIMH). This combination increases serotonin and norepinephrine signaling in the brain through selective serotonin reuptake inhibition and dopamine/norepinephrine reuptake inhibition.

Comparator set (2 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Escitalopram + Bupropion SR TARGET Escitalopram + Bupropion SR National Institute of Mental Health (NIMH) marketed SSRI + NDRI combination Serotonin transporter (SERT); Norepinephrine transporter (NET); Dopamine transporter (DAT)
Paroxetine+Bupropion Paroxetine+Bupropion Ministry of Health & Welfare, Korea marketed SSRI + NDRI combination antidepressant Serotonin transporter (SERT), norepinephrine transporter (NET), dopamine transporter (DAT)
fluoxetine + Amfebutamone fluoxetine + Amfebutamone Shanghai Mental Health Center marketed SSRI + NDRI combination antidepressant Serotonin transporter (SERT), norepinephrine transporter (NET), dopamine transporter (DAT)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (SSRI + NDRI combination class)

  1. National Institute of Mental Health (NIMH) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Escitalopram + Bupropion SR — Competitive Intelligence Brief. https://druglandscape.com/ci/escitalopram-bupropion-sr. Accessed 2026-05-16.

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