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entecavir, lamivudine — Competitive Intelligence Brief
marketed
Nucleoside reverse transcriptase inhibitor (NRTI)
Hepatitis B virus reverse transcriptase
Virology / Hepatology
Small molecule
Live · refreshed every 30 min
Target snapshot
entecavir, lamivudine (entecavir, lamivudine) — Asan Medical Center. Entecavir and lamivudine are nucleoside reverse transcriptase inhibitors that block hepatitis B virus replication by inhibiting the viral reverse transcriptase enzyme.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| entecavir, lamivudine TARGET | entecavir, lamivudine | Asan Medical Center | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase | |
| Blank maleate entecavir tablets | Blank maleate entecavir tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | marketed | Nucleoside reverse transcriptase inhibitor | Hepatitis B virus reverse transcriptase | |
| entecavir (BARACLUDE®) | entecavir (BARACLUDE®) | National Taiwan University Hospital | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase / HBV polymerase | |
| Placebo & Entecavir | Placebo & Entecavir | Fu-Sheng Wang | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase / HBV polymerase | |
| Telbivudine (Standard of Care) | Telbivudine (Standard of Care) | Nanfang Hospital, Southern Medical University | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | Hepatitis B virus reverse transcriptase | |
| Adefovir dipivoxil (adefovir) | Adefovir dipivoxil (adefovir) | Merck Sharp & Dohme LLC | marketed | Nucleotide reverse transcriptase inhibitor | Hepatitis B virus reverse transcriptase / DNA polymerase | |
| Hepsera and lamivudine | Hepsera and lamivudine | University of Washington | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor | Hepatitis B virus reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleoside reverse transcriptase inhibitor (NRTI) class)
- French National Agency for Research on AIDS and Viral Hepatitis · 3 drugs in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- ViiV Healthcare · 2 drugs in this class
- Nanfang Hospital, Southern Medical University · 2 drugs in this class
- Asan Medical Center · 1 drug in this class
- Dong-A ST Co., Ltd. · 1 drug in this class
- Bristol-Myers Squibb · 1 drug in this class
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
- Fu-Sheng Wang · 1 drug in this class
- Avexa · 1 drug in this class
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Cite this brief
Drug Landscape (2026). entecavir, lamivudine — Competitive Intelligence Brief. https://druglandscape.com/ci/entecavir-lamivudine. Accessed 2026-05-16.
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