Last reviewed · How we verify
enfortumab vedotin (EV) — Competitive Intelligence Brief
phase 3
Monoclonal antibody-drug conjugate
Nectin-4
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
enfortumab vedotin (EV) (enfortumab vedotin (EV)) — Astellas Pharma Global Development, Inc.. Enfortumab vedotin is a monoclonal antibody-drug conjugate that targets Nectin-4, a protein highly expressed on the surface of certain cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| enfortumab vedotin (EV) TARGET | enfortumab vedotin (EV) | Astellas Pharma Global Development, Inc. | phase 3 | Monoclonal antibody-drug conjugate | Nectin-4 | |
| Padcev Ejfv | enfortumab-vedotin | Astellas Pharma | marketed | Nectin-4 | 2019-01-01 | |
| ENFORTUMAB VEDOTIN | ENFORTUMAB VEDOTIN | marketed | Nectin-4 | 2019-01-01 | ||
| Enfortumab | padcev | Astellas Pharma | marketed | Nectin-4 | 2019-01-01 | |
| Padcev | AGS-22M6E | Astellas Pharma | marketed | Nectin-4 | 2019-01-01 | |
| Zilovertamab vedotin | Zilovertamab vedotin | Merck Sharp & Dohme LLC | phase 3 | Monoclonal antibody-drug conjugate | CD30 | |
| gemtuzumab ozogamycin | gemtuzumab ozogamycin | Nantes University Hospital | phase 3 | Monoclonal antibody-drug conjugate (ADC) | CD33 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody-drug conjugate class)
- GlaxoSmithKline · 2 drugs in this class
- RemeGen Co., Ltd. · 2 drugs in this class
- Copharos · 1 drug in this class
- Eastern Cooperative Oncology Group · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- Mirati Therapeutics Inc. · 1 drug in this class
- NYU Langone Health · 1 drug in this class
- The Lymphoma Academic Research Organisation · 1 drug in this class
- Astellas Pharma Global Development, Inc. · 1 drug in this class
- Yan Zhang, MD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). enfortumab vedotin (EV) — Competitive Intelligence Brief. https://druglandscape.com/ci/enfortumab-vedotin-ev. Accessed 2026-05-16.
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