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Empasiprubart IV — Competitive Intelligence Brief
phase 3
FcRn antagonist
FcRn (neonatal Fc receptor)
Immunology
Biologic
Live · refreshed every 30 min
Target snapshot
Empasiprubart IV (Empasiprubart IV) — argenx. Empasiprubart is a FcRn (neonatal Fc receptor) antagonist that reduces the recycling and extends the half-life of IgG antibodies, enhancing their therapeutic activity.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Empasiprubart IV TARGET | Empasiprubart IV | argenx | phase 3 | FcRn antagonist | FcRn (neonatal Fc receptor) | |
| Efgartigimod PH20 SC | Efgartigimod PH20 SC | argenx | marketed | FcRn antagonist | Neonatal Fc receptor (FcRn) | |
| UPLIZNA | UPLIZNA | Amgen | marketed | FcRn antagonist | FcRn (neonatal Fc receptor) | |
| IMVT-1402 | IMVT-1402 | Immunovant Sciences GmbH | phase 3 | FcRn antagonist | FcRn (neonatal Fc receptor) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (FcRn antagonist class)
- argenx · 2 drugs in this class
- Amgen · 1 drug in this class
- Immunovant Sciences GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Empasiprubart IV — Competitive Intelligence Brief. https://druglandscape.com/ci/empasiprubart-iv. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing