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ELV/COBI/FTC/TAF — Competitive Intelligence Brief
marketed
Antiretroviral combination therapy (integrase inhibitor + NRTI + NtRTI + pharmacokinetic booster)
HIV integrase, HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
ELV/COBI/FTC/TAF (ELV/COBI/FTC/TAF) — Fundacion SEIMC-GESIDA. This is a fixed-dose combination of four antiretroviral agents that work together to suppress HIV replication through multiple mechanisms: elvitegravir inhibits integrase, cobicistat boosts drug levels, and emtricitabine and tenofovir alafenamide inhibit reverse transcriptase.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ELV/COBI/FTC/TAF TARGET | ELV/COBI/FTC/TAF | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination therapy (integrase inhibitor + NRTI + NtRTI + pharmacokinetic booster) | HIV integrase, HIV reverse transcriptase | |
| Biktarvy 50/200/25 Tab | Biktarvy 50/200/25 Tab | Radboud University Medical Center | marketed | Antiretroviral combination (integrase inhibitor + nucleotide/nucleoside reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| Bictegravir, emtricitabine, and tenofovir alafenamide | Bictegravir, emtricitabine, and tenofovir alafenamide | CAN Community Health | marketed | Antiretroviral combination (integrase inhibitor + nucleoside reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| DTG/ABC/3TC | DTG/ABC/3TC | Harvard School of Public Health (HSPH) | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| B/FTC/TAF | B/FTC/TAF | The University of Texas Health Science Center, Houston | marketed | Antiretroviral combination (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| Raltegravir, tenofovir/emtricitabine | Raltegravir, tenofovir/emtricitabine | University of California, San Francisco | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| dolutegravir/abacavir/lamivudine | dolutegravir/abacavir/lamivudine | University College Dublin | marketed | Antiretroviral combination (INSTI + NRTIs) | HIV integrase, HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (integrase inhibitor + NRTI + NtRTI + pharmacokinetic booster) class)
- Fundacion SEIMC-GESIDA · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ELV/COBI/FTC/TAF — Competitive Intelligence Brief. https://druglandscape.com/ci/elv-cobi-ftc-taf. Accessed 2026-05-14.
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