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Rhgalns — Competitive Intelligence Brief
marketed
Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC]
N-acetylgalactosamine-6-sulfatase
Metabolic
Enzyme
Live · refreshed every 30 min
Target snapshot
Rhgalns (ELOSULFASE ALFA) — BioMarin. VIMIZIM provides exogenous N-acetylgalactosamine-6-sulfatase to increase the catabolism of GAGs KS and C6S in lysosomes.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rhgalns TARGET | ELOSULFASE ALFA | BioMarin | marketed | Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] | N-acetylgalactosamine-6-sulfatase | 2014-01-01 |
| BMN 165 | BMN 165 | BioMarin Pharmaceutical | phase 3 | Gene therapy (AAV-based) | GALNS gene (N-acetylgalactosamine-6-sulfatase) | |
| Elaprase | IDURSULFASE | Takeda | marketed | Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] | 2006-01-01 | |
| Aryplase | GALSULFASE | BioMarin | marketed | Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] | 2005-01-01 | |
| Aldurazyme | LARONIDASE | BioMarin | marketed | Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] | 2003-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme [EPC] class)
- BioMarin · 3 drugs in this class
- Takeda · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rhgalns — Competitive Intelligence Brief. https://druglandscape.com/ci/elosulfase-alfa. Accessed 2026-05-16.
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