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Eflornithine plus Sulindac — Competitive Intelligence Brief
phase 3
Polyamine synthesis inhibitor + NSAID combination
Ornithine decarboxylase (ODC); COX-1/COX-2
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Eflornithine plus Sulindac (Eflornithine plus Sulindac) — Cancer Prevention Pharmaceuticals, Inc.. Eflornithine inhibits polyamine synthesis while sulindac acts as a non-selective NSAID to reduce inflammation and promote apoptosis, together targeting colorectal cancer prevention.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Eflornithine plus Sulindac TARGET | Eflornithine plus Sulindac | Cancer Prevention Pharmaceuticals, Inc. | phase 3 | Polyamine synthesis inhibitor + NSAID combination | Ornithine decarboxylase (ODC); COX-1/COX-2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Polyamine synthesis inhibitor + NSAID combination class)
- Cancer Prevention Pharmaceuticals, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Eflornithine plus Sulindac — Competitive Intelligence Brief. https://druglandscape.com/ci/eflornithine-plus-sulindac. Accessed 2026-05-17.
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