Who are EFI/ACT-385781A's main competitors?

No direct comparators detected in our index.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

EFI/ACT-385781A — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

EFI/ACT-385781A (EFI/ACT-385781A) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective endothelin receptor antagonist. Area: Cardiovascular.

phase 3 Selective endothelin receptor antagonist Endothelin receptor (ETA/ETB) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

EFI/ACT-385781A (EFI/ACT-385781A) — Actelion. EFI/ACT-385781A is a selective endothelin receptor antagonist that blocks endothelin-1 signaling to reduce pulmonary vascular resistance and improve hemodynamics.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
EFI/ACT-385781A TARGET	EFI/ACT-385781A	Actelion	phase 3	Selective endothelin receptor antagonist	Endothelin receptor (ETA/ETB)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective endothelin receptor antagonist class)

Actelion · 1 drug in this class

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Cite this brief

Drug Landscape (2026). EFI/ACT-385781A — Competitive Intelligence Brief. https://druglandscape.com/ci/efi-act-385781a. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing