Efficacy of ceftaroline — Competitive Intelligence Brief

Efficacy of ceftaroline (Efficacy of ceftaroline) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Fifth-generation cephalosporin. Area: Infectious Disease.

phase 3 Fifth-generation cephalosporin Bacterial penicillin-binding proteins Infectious Disease Small molecule

Target snapshot

Efficacy of ceftaroline (Efficacy of ceftaroline) — Albany Medical College. Ceftaroline is a fifth-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Efficacy of ceftaroline TARGET	Efficacy of ceftaroline	Albany Medical College	phase 3	Fifth-generation cephalosporin	Bacterial penicillin-binding proteins
Co-amoxiclav	Co-amoxiclav	Imperial College London	marketed	Beta-lactam antibiotic with beta-lactamase inhibitor	Bacterial penicillin-binding proteins (PBPs); bacterial beta-lactamases
Ceftazidime-avibactam + Sulbactam	Ceftazidime-avibactam + Sulbactam	National University of Singapore	marketed	Beta-lactam/beta-lactamase inhibitor combination	Bacterial penicillin-binding proteins (PBPs); serine beta-lactamases
CAZ/AVI	CAZ/AVI	The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School	marketed	Beta-lactam/beta-lactamase inhibitor combination	Bacterial penicillin-binding proteins (PBPs); serine beta-lactamases
Imipenem/Cilastatin/Relebactam	Imipenem/Cilastatin/Relebactam	Evopoint Biosciences Inc.	marketed	Carbapenem antibiotic with beta-lactamase inhibitor	Bacterial penicillin-binding proteins; serine beta-lactamases
Ceftolozane / Tazobactam Injection	Ceftolozane / Tazobactam Injection	Weill Medical College of Cornell University	marketed	Beta-lactam / beta-lactamase inhibitor combination	Bacterial penicillin-binding proteins; beta-lactamase enzymes
Cefazolin + Gentamicin	Cefazolin + Gentamicin	Mercy Health Ohio	marketed	Beta-lactam antibiotic + aminoglycoside antibiotic combination	Bacterial penicillin-binding proteins (cefazolin); bacterial 30S ribosomal subunit (gentamicin)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Fifth-generation cephalosporin class)

1. Albany Medical College · 1 drug in this class