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Eculizumab Injection — Competitive Intelligence Brief

Eculizumab Injection (Eculizumab Injection) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Complement C5 inhibitor. Area: Immunology.

phase 3 Complement C5 inhibitor C5 (Complement protein 5) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Eculizumab Injection (Eculizumab Injection) — Wuhan Createrna Science and Technology Co., Ltd. Eculizumab is a monoclonal antibody that inhibits the complement protein C5, blocking the formation of the membrane attack complex and reducing complement-mediated cell destruction.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Eculizumab Injection TARGET Eculizumab Injection Wuhan Createrna Science and Technology Co., Ltd phase 3 Complement C5 inhibitor C5 (Complement protein 5)
Piasky CROVALIMAB Genentech Inc marketed Complement C5 Inhibitor [EPC] 2025-01-01
PIASKY CROVALIMAB-AKKZ GENENTECH INC marketed Complement C5 Inhibitor [EPC]
Eculizumab (Soliris®) Eculizumab (Soliris®) Massachusetts General Hospital marketed Complement C5 inhibitor Complement protein C5
C5 Inhibitor C5 Inhibitor Alexion Pharmaceuticals, Inc. phase 3 Complement C5 inhibitor C5
BOL-303259-X BOL-303259-X Bausch & Lomb Incorporated phase 3 Complement C5 inhibitor Complement C5
Spacing of Eculizumab infusions Spacing of Eculizumab infusions University Hospital, Tours phase 3 Complement C5 inhibitor Complement protein C5

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Complement C5 inhibitor class)

  1. Alexion Pharmaceuticals, Inc. · 1 drug in this class
  2. Bausch & Lomb Incorporated · 1 drug in this class
  3. Massachusetts General Hospital · 1 drug in this class
  4. University Hospital, Tours · 1 drug in this class
  5. Wuhan Createrna Science and Technology Co., Ltd · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Eculizumab Injection — Competitive Intelligence Brief. https://druglandscape.com/ci/eculizumab-injection. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing