Who are Kalbitor's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Orladeyo, BEROTRALSTAT HYDROCHLORIDE, Takhzyro, TAKHZYRO, C1 Esterase Inhibitor (Human), BCX7353 capsules.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Kalbitor — Competitive Intelligence Brief

Kalbitor (ECALLANTIDE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Plasma Kallikrein Inhibitor [EPC]. Area: Neuroscience.

marketed Plasma Kallikrein Inhibitor [EPC] Plasma kallikrein Neuroscience Recombinant protein Live · refreshed every 30 min

Target snapshot

Kalbitor (ECALLANTIDE) — Dyax Corp.. Kalbitor works by blocking the plasma kallikrein enzyme, which is involved in the production of bradykinin, a key mediator of HAE symptoms.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Kalbitor TARGET	ECALLANTIDE	Dyax Corp.	marketed	Plasma Kallikrein Inhibitor [EPC]	Plasma kallikrein	2009-01-01
Orladeyo	BEROTRALSTAT	Biocryst	marketed	Plasma Kallikrein Inhibitor	Plasma kallikrein	2020-01-01
BEROTRALSTAT HYDROCHLORIDE	BEROTRALSTAT HYDROCHLORIDE		marketed		plasma kallikrein	2020-01-01
Takhzyro	LANADELUMAB	Dyax Corp	marketed	Plasma Kallikrein Inhibitor [EPC]	plasma kallikrein	2018-01-01
TAKHZYRO	LANADELUMAB-FLYO	DYAX CORP.	marketed	Plasma Kallikrein Inhibitor [EPC]	Plasma kallikrein
C1 Esterase Inhibitor (Human)	C1 Esterase Inhibitor (Human)	Shire	marketed	Serine protease inhibitor; complement regulator	C1 esterase inhibitor (C1-INH); Factor XIIa; plasma kallikrein
BCX7353 capsules	BCX7353 capsules	BioCryst Pharmaceuticals	phase 3	Plasma kallikrein inhibitor	Plasma kallikrein (Factor XIa)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Plasma Kallikrein Inhibitor [EPC] class)

DYAX CORP. · 1 drug in this class
Dyax Corp · 1 drug in this class
Dyax Corp. · 1 drug in this class
Kalvista · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Kalbitor — Competitive Intelligence Brief. https://druglandscape.com/ci/ecallantide. Accessed 2026-05-13.

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