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Durvalumab plus chemotherapy — Competitive Intelligence Brief

Durvalumab plus chemotherapy (Durvalumab plus chemotherapy) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PD-L1 inhibitor plus chemotherapy combination. Area: Oncology.

phase 3 PD-L1 inhibitor plus chemotherapy combination PD-L1 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Durvalumab plus chemotherapy (Durvalumab plus chemotherapy) — AstraZeneca. Durvalumab blocks PD-L1 to restore anti-tumor immunity, while chemotherapy directly kills cancer cells and enhances immune activation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Durvalumab plus chemotherapy TARGET Durvalumab plus chemotherapy AstraZeneca phase 3 PD-L1 inhibitor plus chemotherapy combination PD-L1
AVELUMAB AVELUMAB marketed Programmed Death Ligand-1 Blocker [EPC] PD-L1 2017-01-01
DURVALUMAB DURVALUMAB marketed Programmed Death Ligand-1 Blocker [EPC] PD-L1 2017-01-01
PD-1 / PD-L1 monoclonal antibody PD-1 / PD-L1 monoclonal antibody Cancer Institute and Hospital, Chinese Academy of Medical Sciences marketed PD-1/PD-L1 inhibitor PD-1 and/or PD-L1
Cisplatin / Carboplatin,Gemcitabine,Cindilimab Cisplatin / Carboplatin,Gemcitabine,Cindilimab People's Hospital of Quzhou marketed Combination chemotherapy with immune checkpoint inhibitor DNA (platinum agents, gemcitabine); PD-L1 (cindilimab)
AB AB GlaxoSmithKline marketed PD-L1 inhibitor PD-L1
Pf-06835375 pf-06835375 Pfizer marketed Immunotherapy PD-L1

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PD-L1 inhibitor plus chemotherapy combination class)

  1. AstraZeneca · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Durvalumab plus chemotherapy — Competitive Intelligence Brief. https://druglandscape.com/ci/durvalumab-plus-chemotherapy. Accessed 2026-05-16.

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