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Durvalumab + Olaparib phase — Competitive Intelligence Brief
phase 3
PD-L1 inhibitor + PARP inhibitor combination
PD-L1 and PARP1/PARP2
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Durvalumab + Olaparib phase (Durvalumab + Olaparib phase) — AstraZeneca. Durvalumab blocks PD-L1 to enhance immune activation while olaparib inhibits PARP to impair DNA repair, together leveraging immunotherapy and synthetic lethality in homologous recombination-deficient tumors.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Durvalumab + Olaparib phase TARGET | Durvalumab + Olaparib phase | AstraZeneca | phase 3 | PD-L1 inhibitor + PARP inhibitor combination | PD-L1 and PARP1/PARP2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PD-L1 inhibitor + PARP inhibitor combination class)
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Durvalumab + Olaparib phase — Competitive Intelligence Brief. https://druglandscape.com/ci/durvalumab-olaparib-phase. Accessed 2026-06-10.
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